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1 July 2010 Parametric imaging of cancer with optical coherence tomography
Robert A. McLaughlin, Loretta Scolaro, Peter Robbins, Christobel Saunders, Steven L. Jacques, David D. Sampson
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Journal of Biomedical Optics, Vol. 15, Issue 4, 046029 (July 2010). https://doi.org/10.1117/1.3479931
Abstract
We present a parametric optical coherence tomography (OCT) technique to improve contrast between malignant and healthy non-neoplastic tissue. The technique incorporates a fully automated method to extract tissue attenuation characteristics. Results are represented visually as a parametric en face image, where the parameter used for contrast is indicative of the relative optical attenuation coefficient of the tissue. We present the first parametric OCT images of human lymph nodes containing malignant cells, and demonstrate improved tissue contrast over en face OCT images.
©(2010) Society of Photo-Optical Instrumentation Engineers (SPIE)
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Robert A. McLaughlin, Loretta Scolaro, Peter Robbins, Christobel Saunders, Steven L. Jacques, and David D. Sampson "Parametric imaging of cancer with optical coherence tomography," Journal of Biomedical Optics 15(4), 046029 (1 July 2010). https://doi.org/10.1117/1.3479931
Published: 1 July 2010
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Cited by 59 scholarly publications and 3 patents.
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KEYWORDS
Optical coherence tomography
Tissues
Lymphatic system
Signal attenuation
Tissue optics
Cancer
Glasses
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