CONFERENCE PROCEEDINGS
Advanced Search
Home > Journals > J. Biomed. Opt. > Volume 16 > Issue 4 > Article
Open Access
1 April 2011 Visualization of light propagation in visible Chinese human head for functional near-infrared spectroscopy
Ting Li, Hui Gong, Qingming Luo
Author Affiliations +
Journal of Biomedical Optics, Vol. 16, Issue 4, 045001 (April 2011). https://doi.org/10.1117/1.3567085
Abstract
Using the visible Chinese human data set, which faithfully represents human anatomy, we visualize the light propagation in the head in detail based on Monte Carlo simulation. The simulation is verified to agree with published experimental results in terms of a differential path-length factor. The spatial sensitivity profile turns out to seem like a fat tropical fish with strong distortion along the folding cerebral surface. The sensitive brain region covers the gray matter and extends to the superficial white matter, leading to a large penetration depth (<3 cm). Finally, the optimal source-detector separation is suggested to be narrowed down to 3-3.5 cm, while the sensitivity of the detected signal to brain activation reaches the peak of 8%. These results indicate that the cerebral cortex folding geometry actually has substantial effects on light propagation, which should be necessarily considered for applications of functional near-infrared spectroscopy.
©(2011) Society of Photo-Optical Instrumentation Engineers (SPIE)
Citation Download Citation
Ting Li, Hui Gong, and Qingming Luo "Visualization of light propagation in visible Chinese human head for functional near-infrared spectroscopy," Journal of Biomedical Optics 16(4), 045001 (1 April 2011). https://doi.org/10.1117/1.3567085
Published: 1 April 2011
JOURNAL ARTICLE
 7 PAGES
DOWNLOAD PAPER SAVE TO MY LIBRARY
GET CITATION
Lens.org Logo
CITATIONS
Cited by 79 scholarly publications.
Advertisement
Advertisement
RIGHTS & PERMISSIONS
Get copyright permission  Get copyright permission on Copyright Marketplace
KEYWORDS
Head
Brain
Signal detection
Cerebral cortex
Monte Carlo methods
Tissues
Visible radiation
RELATED CONTENT
Subscribe to Digital Library
Receive Erratum Email Alert
Back to Top