We explore the practical limits for wave optics simulations of plane-wave propagation in non-Kolmogorov turbulence using the split-step method and thin phase screens. These limits inform two simulation campaigns where the relationship between volume turbulence strength and normalized intensity variance for various non-Kolmogorov power laws is explored. We find that simulation of power-law exponents near 3 are limited to turbulence strengths with Rytov numbers of 7 when the simulation side-length sampling rate is limited to 8192. Under these same conditions, it is possible to simulate volume turbulence strength out to Rytov numbers of 12 for Kolmogorov turbulence out to a power-law exponent of 4. We also demonstrate that the peak scintillation and Rytov number where peak scintillation occurs increases approximately linearly with the power-law exponent. Also, if turbulence strength is fixed, the relationship between the scintillation index and power law depends on the operating regime. In weak turbulence, the relationship is negative, and it is positive in strong turbulence. This work also emphasizes the importance of properly scaling turbulence strength when comparing results between different mediums with different power laws and the influence and importance of defining inner and outer scales in these simulations.