Paper
1 March 2019 Use of machine learning in CARNA proton imager
Gabriel Varney, Catherine Dema, Burak E. Gul, Collin J. Wilkinson, Ugur Akgun
Author Affiliations +
Abstract
Proton therapy has potential for high precision dose delivery, provided that high accuracy is achieved in imaging. Currently, X-ray based techniques are preferred for imaging prior to proton therapy, and the stopping power conversion tables cause irreducible uncertainty. The proposed proton imaging methods aim to reduce this source of error, as well as lessen the radiation exposure of the patient. CARNA is a homogeneous compact calorimeter that utilizes a novel highdensity scintillating glass as an active medium. The compact design and unique geometry of the calorimeter eliminate the need for a tracker system and allow it to be directly attached to a gantry. Thus, giving CARNA potential to be used for insitu imaging during the hadron therapy, possibly to detect the prompt gammas. The novel glass development and the traditional image reconstruction studies performed with CARNA have been reported before. However, to improve the image reconstruction, a machine learning implementation with CARNA is reported. A proof-of-concept Artificial Neural Network, is shown to efficiently predict the density and the shape of the tumors.
© (2019) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Gabriel Varney, Catherine Dema, Burak E. Gul, Collin J. Wilkinson, and Ugur Akgun "Use of machine learning in CARNA proton imager", Proc. SPIE 10948, Medical Imaging 2019: Physics of Medical Imaging, 109485P (1 March 2019); https://doi.org/10.1117/12.2512565
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KEYWORDS
Glasses

Image restoration

Machine learning

Computed tomography

Tumors

Neural networks

Imaging systems

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