Holographic optical probing of the computing properties of single neurons

Vincent Daria

doi:10.1117/12.2615421

27 October 2021 Holographic optical probing of the computing properties of single neurons

Vincent Daria

Proceedings Volume 11925, Biomedical Imaging and Sensing Conference 2021; 119250D (2021) https://doi.org/10.1117/12.2615421
Event: SPIE Technologies and Applications of Structured Light, 2021, Online, Japan

Abstract

Neurons receive synaptic inputs via its dendrites and understanding the processing of those inputs as well as the influence of the dendrite’s non-linear properties are key components to decode the neuron’s computing power. Recent breakthroughs to understand dendritic function make use holographic structured illumination to stimulate and/or record dendritic activity either via photochemical or optogenetic tools. In this talk, I will summarize our efforts where we used holograms to probe the integrative and non-linear properties of dendrites of a neuron. Understanding the role of dendrites in neuronal function offer significant insights as to how these neurons function as tiny computers in the brain.

Citation Download Citation

Vincent Daria "Holographic optical probing of the computing properties of single neurons", Proc. SPIE 11925, Biomedical Imaging and Sensing Conference 2021, 119250D (27 October 2021); https://doi.org/10.1117/12.2615421

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