Applications of CRISPR/Cas9 gene-editing technology in cancer

Chihan Wang

doi:10.1117/12.3013218

8 January 2024 Applications of CRISPR/Cas9 gene-editing technology in cancer

Chihan Wang

Proceedings Volume 12924, Third International Conference on Biological Engineering and Medical Science (ICBioMed2023); 1292423 (2024) https://doi.org/10.1117/12.3013218
Event: 3rd International Conference on Biological Engineering and Medical Science (ICBioMed2023), 2023, ONLINE, United Kingdom

Abstract

Cancer has been a problematic disorder for many years, many people will develop cancer sometime in their life but there are few ways to cure it. Treatment for cancer in the modern era is a painful and expensive process with no guarantee that it will not come back. It significantly impacts the life quality and life expectancy of patients. However, the discovery of genetic editing techniques such as CRISPR/CAS9 have opened a new way to cure cancer. Since cancer is a genetic disorder, genetic editing techniques have the possibility to solve it at the genetic level. While other treatments simply get rid of the tumor by using tools such as laser and surgery knife, gene therapy can use the patient's own immune system to battle against cancer. Moreover, there are multiple delivery methods to deliver CRISPR/CAS9 into the cell, each with their own advantages and disadvantages. However, since the genetic editing technique CRISPR/CAS9 is not advanced enough to use on patients, the only clinical use of CRISPR/Cas9 is on T cells in the patient's blood. This article introduces the current research status on CRISPR/CAS9 delivery platforms and clinical use of genetic editing techniques in treatment of cancer.

(2024) Published by SPIE. Downloading of the abstract is permitted for personal use only.

Citation Download Citation

Chihan Wang "Applications of CRISPR/Cas9 gene-editing technology in cancer", Proc. SPIE 12924, Third International Conference on Biological Engineering and Medical Science (ICBioMed2023), 1292423 (8 January 2024); https://doi.org/10.1117/12.3013218

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