Laser-induced heat-diffusion-limited tissue coagulation: I. Form of the necrosis boundary caused by random temperature nonuniformities

Igor A. Lubashevsky; Alexander V. Priezzhev

doi:10.1117/12.297895

14 January 1998 Laser-induced heat-diffusion-limited tissue coagulation: I. Form of the necrosis boundary caused by random temperature nonuniformities

Igor A. Lubashevsky, Alexander V. Priezzhev

Author Affiliations +

Proceedings Volume 3195, Laser-Tissue Interaction, Tissue Optics, and Laser Welding III; (1998) https://doi.org/10.1117/12.297895
Event: BiOS Europe '97, 1997, San Remo, Italy

Abstract

When heated the living tissue exhibits random nonuniformities in the temperature that are due to the discreetness of vessel arrangement. Because of strong temperature dependence of the thermal coagulation rate these nonuniformities should substantially affect the necrosis growth induced by local heating. In the present work we study their effect on the form of a necrosis domain when its growth is limited by heat diffusion into the surrounding tissue. In particular, we analyze the mean amplitude and the correlation length of the interface perturbations depending on the main characteristics of the random temperature nonuniformities.

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Igor A. Lubashevsky and Alexander V. Priezzhev "Laser-induced heat-diffusion-limited tissue coagulation: I. Form of the necrosis boundary caused by random temperature nonuniformities", Proc. SPIE 3195, Laser-Tissue Interaction, Tissue Optics, and Laser Welding III, (14 January 1998); https://doi.org/10.1117/12.297895

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