Subcutaneous adipose tissue topography (SAT-Top) by means of the optical device lipometer highly correlated to plasma leptin levels in obese boys

Karl Sudi; Reinhard Moeller; Erwin Tafeit; Elke Reiterer; Martin Borkenstein; Karoline Vrecko; Renate Horejsi; Gilbert Reibnegger; Peter Hofmann

doi:10.1117/12.308194

13 May 1998 Subcutaneous adipose tissue topography (SAT-Top) by means of the optical device lipometer highly correlated to plasma leptin levels in obese boys

Karl Sudi, Reinhard Moeller, Erwin Tafeit, Elke Reiterer, Martin Borkenstein, Karoline Vrecko, Renate Horejsi, Gilbert Reibnegger, Peter Hofmann

Author Affiliations +

Proceedings Volume 3254, Laser-Tissue Interaction IX; (1998) https://doi.org/10.1117/12.308194
Event: BiOS '98 International Biomedical Optics Symposium, 1998, San Jose, CA, United States

Abstract

The product of the ob-gene named leptin is correlated with body fat mass in humans. Little evidence exists if the same holds true for body fat distribution. In this study we therefore investigated plasma leptin levels and the subcutaneous adipose tissue topography (SAT-Top) by means of the newly developed optical device Lipometer before and after a 3 week weight reduction camp. Thirty four obese boys (mean age 12a) took part in this study. Body fat distribution were assessed by means of Lipometer to measure the thickness of a subcutaneous fat layer at 15 standardized body sites (SAT- Top). Plasma leptin levels (LL) were measured by radioimmunoassay. All measurements were taken at the beginning and at the end of the camp. By dividing all boys according chronological age (group A: age less than 12a, n equals 17/group B: greater than 12a, n equals 17) we found correlations with the combination of measured body sites (MBS) before (A: MBS vs. LL, R² equals 0.79; p less than 0.01/B: MBS vs. LL, R² equals 0.35; n.s.) and after (A: MBS vs. LL, R² equals 0.83; p less than 0.01/B: MBS vs. LL, R² equals 0.70; p less than 0.01) the intervention. Our study confirms that the subcutaneous adipose tissue topography (SAT- Top) by means of the optical device Lipometer serves as a marker of plasma leptin levels in obese boys and highlights the use of this optical device in a predictive manner.

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Karl Sudi, Reinhard Moeller, Erwin Tafeit, Elke Reiterer, Martin Borkenstein, Karoline Vrecko, Renate Horejsi, Gilbert Reibnegger, and Peter Hofmann "Subcutaneous adipose tissue topography (SAT-Top) by means of the optical device lipometer highly correlated to plasma leptin levels in obese boys", Proc. SPIE 3254, Laser-Tissue Interaction IX, (13 May 1998); https://doi.org/10.1117/12.308194

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KEYWORDS

Optical components

Plasma

Tissue optics

Tissues

Computed tomography

Magnetic resonance imaging

Near infrared

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