Imaging of spatio-temporal coincident states by dynamic optical tomography

Harry L. Graber; Yaling Pei; Randall Locke Barbour

doi:10.1117/12.434487

29 June 2001 Imaging of spatio-temporal coincident states by dynamic optical tomography

Harry L. Graber, Yaling Pei, Randall Locke Barbour

Proceedings Volume 4250, Optical Tomography and Spectroscopy of Tissue IV; (2001) https://doi.org/10.1117/12.434487
Event: BiOS 2001 The International Symposium on Biomedical Optics, 2001, San Jose, CA, United States

Abstract

The utility of optical tomography as a static imaging modality is limited by its intrinsically low spatial resolution and quantitative accuracy. When applied to dynamic measurements, however, optical imaging methods have the potential to assess tissue function as revealed by temporal variations in tissue optical properties. These variations are a consequence of vascular hemodynamic processes, which are known to exhibit considerably spatiotemporal heterogeneity. In this report we provide evidence, from simulation, that complex dynamic behavior in optical coefficients occurring in localized regions in highly scattering media can be accurately characterized by the method of dynamic optical tomography, even in the limiting case of spatiotemporally coincident behavior.

Citation Download Citation

Harry L. Graber, Yaling Pei, and Randall Locke Barbour "Imaging of spatio-temporal coincident states by dynamic optical tomography", Proc. SPIE 4250, Optical Tomography and Spectroscopy of Tissue IV, (29 June 2001); https://doi.org/10.1117/12.434487

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