Spectral analysis of optical imaging through blood

Valentin M. Grimblatov; Daniel C. Lee; Mehmet Cengiz Oz M.D.; Edward F. Leonard

doi:10.1117/12.431785

17 June 2002 Spectral analysis of optical imaging through blood

Valentin M. Grimblatov, Daniel C. Lee, Mehmet Cengiz Oz M.D., Edward F. Leonard

Proceedings Volume 4609, Lasers in Surgery: Advanced Characterization, Therapeutics, and Systems XII; (2002) https://doi.org/10.1117/12.431785
Event: International Symposium on Biomedical Optics, 2002, San Jose, CA, United States

Abstract

We present theoretical calculations and experimental imaging results that demonstrate the possibility of extending viewing distances through blood simply by selection of an ‘optimal’ illuminating wavelength and use of a camera with appropriate parameters. Based on a simple one-dimensional model of image signal formation and employing Kubelka- Munk theory of light transport in a turbid medium, we derive an analytical expression that describes the effect of optical properties of the medium and camera parameters on image signal. Experimental images of an artificial target placed behind a sample of human blood of different thickness taken in transmission and reflection modes confirm the predicted imaging possibilities. An optical-difference offset technique developed to enhance image contrast is demonstrated as well.

Citation Download Citation

Valentin M. Grimblatov, Daniel C. Lee, Mehmet Cengiz Oz M.D., and Edward F. Leonard "Spectral analysis of optical imaging through blood", Proc. SPIE 4609, Lasers in Surgery: Advanced Characterization, Therapeutics, and Systems XII, (17 June 2002); https://doi.org/10.1117/12.431785

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