Noninvasive measurement of intracellular viscoelastic properties

Martha B. Alvarez-Elizondo; Susan H. Roelofs; Frederic A. Meunier; Norman Heckenberg; Halina Rubinsztein-Dunlop

doi:10.1117/12.793591

29 August 2008 Noninvasive measurement of intracellular viscoelastic properties

Martha B. Alvarez-Elizondo, Susan H. Roelofs, Frederic A. Meunier, Norman Heckenberg, Halina Rubinsztein-Dunlop

Proceedings Volume 7038, Optical Trapping and Optical Micromanipulation V; 70380D (2008) https://doi.org/10.1117/12.793591
Event: NanoScience + Engineering, 2008, San Diego, California, United States

Abstract

We are exploring a biological application of optical tweezers with fluorescence imaging for microrheometry. Measurement of the power spectrum of Brownian motion of a trapped probe particle or vesicle provides information on the viscoelastic properties of the surrounding medium which can change in response to cellular processes or the effect of drugs.

Citation Download Citation

Martha B. Alvarez-Elizondo, Susan H. Roelofs, Frederic A. Meunier, Norman Heckenberg, and Halina Rubinsztein-Dunlop "Noninvasive measurement of intracellular viscoelastic properties", Proc. SPIE 7038, Optical Trapping and Optical Micromanipulation V, 70380D (29 August 2008); https://doi.org/10.1117/12.793591

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