Experimental retinectomy with a 6.1 µm Q-switched Raman-shifted alexandrite laser

Karen M. Joos; Ratna Prasad; John Kozub; Borislav Ivanov; Anita Agarwal; Jin H. Shen

doi:10.1117/12.846890

2 March 2010 Experimental retinectomy with a 6.1 μm Q-switched Raman-shifted alexandrite laser

Karen M. Joos, Ratna Prasad, John Kozub, Borislav Ivanov, Anita Agarwal, Jin H. Shen

Proceedings Volume 7550, Ophthalmic Technologies XX; 75500X (2010) https://doi.org/10.1117/12.846890
Event: SPIE BiOS, 2010, San Francisco, California, United States

Abstract

Purpose: It is hypothesized that 6.1 μm produced by a portable laser would be useful for incising tissue layers such as performing a retinectomy in detached retina with extensive anterior proliferative vitreoretinopathy. Methods: An alexandrite laser system, which provides a high-intensity Q-switched pulse (780 nm, 50-100 ns duration, 10 Hz), is wavelength-shifted by a two-stage stimulated Raman conversion process into the 6-7 μm range (Light Age, Inc.). Fresh cadaver porcine retinas were lased with 6.1 μm using a 200 μm diameter spot at 0.6 mJ after removal of the vitreous. Specimens were examined grossly and prepared for histological examination. Results: The Raman-shifted alexandrite laser produced a smooth Gaussian profile. A narrow spectrum was produced at 6.1 μm. A full-thickness retinal incision with minimal thermal damage was obtained at a low energy level of 0.6 mJ in the retinas. However, the depth of the incision did vary from an incomplete incision to a full-thickness incision involving the underlying choroidal layer in attached retinas. Conclusions: The 6.1 μm mid-infrared energy produced by a portable laser is capable of incising detached retinas with minimal thermal damage.

Citation Download Citation

Karen M. Joos, Ratna Prasad, John Kozub, Borislav Ivanov, Anita Agarwal, and Jin H. Shen "Experimental retinectomy with a 6.1 μm Q-switched Raman-shifted alexandrite laser", Proc. SPIE 7550, Ophthalmic Technologies XX, 75500X (2 March 2010); https://doi.org/10.1117/12.846890

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