A femtosecond laser inscribed biochip for stem cell therapeutic applications

D. Choudhury; W. T. Ramsay; G. Brown; N. D. Psaila; S. Beecher; R. R. Thomson; R. Kiss; S. Pells; N. A. Willoughby; L. Paterson; A. K. Kar

doi:10.1117/12.874954

14 February 2011 A femtosecond laser inscribed biochip for stem cell therapeutic applications

D. Choudhury, W. T. Ramsay, G. Brown, N. D. Psaila, S. Beecher, R. R. Thomson, R. Kiss, S. Pells, N. A. Willoughby, L. Paterson, A. K. Kar

Author Affiliations +

Proceedings Volume 7929, Microfluidics, BioMEMS, and Medical Microsystems IX; 79290P (2011) https://doi.org/10.1117/12.874954
Event: SPIE MOEMS-MEMS, 2011, San Francisco, California, United States

Abstract

A continuous flow microfluidic cell separation platform has been designed and fabricated using femtosecond laser inscription. The device is a scalable and non-invasive cell separation mechanism aimed at separating human embryonic stem cells from differentiated cells based on the dissimilarities in their cytoskeletal elasticity. Successful demonstration of the device has been achieved using human leukemia cells the elasticity of which is similar to that of human embryonic stem cells.

Citation Download Citation

D. Choudhury, W. T. Ramsay, G. Brown, N. D. Psaila, S. Beecher, R. R. Thomson, R. Kiss, S. Pells, N. A. Willoughby, L. Paterson, and A. K. Kar "A femtosecond laser inscribed biochip for stem cell therapeutic applications", Proc. SPIE 7929, Microfluidics, BioMEMS, and Medical Microsystems IX, 79290P (14 February 2011); https://doi.org/10.1117/12.874954

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