Color-matched esophagus phantom for fluorescent imaging

Chenying Yang; Vivian Hou; Leonard Y. Nelson; Eric J. Seibel

doi:10.1117/12.2000834

28 February 2013 Color-matched esophagus phantom for fluorescent imaging

Chenying Yang, Vivian Hou, Leonard Y. Nelson, Eric J. Seibel

Proceedings Volume 8583, Design and Performance Validation of Phantoms Used in Conjunction with Optical Measurement of Tissue V; 85830F (2013) https://doi.org/10.1117/12.2000834
Event: SPIE BiOS, 2013, San Francisco, California, United States

Abstract

We developed a stable, reproducible three-dimensional optical phantom for the evaluation of a wide-field endoscopic molecular imaging system. This phantom mimicked a human esophagus structure with flexibility to demonstrate body movements. At the same time, realistic visual appearance and diffuse spectral reflectance properties of the tissue were simulated by a color matching methodology. A photostable dye-in-polymer technology was applied to represent biomarker probed “hot-spot” locations. Furthermore, fluorescent target quantification of the phantom was demonstrated using a 1.2mm ultrathin scanning fiber endoscope with concurrent fluorescence-reflectance imaging.

Citation Download Citation

Chenying Yang, Vivian Hou, Leonard Y. Nelson, and Eric J. Seibel "Color-matched esophagus phantom for fluorescent imaging", Proc. SPIE 8583, Design and Performance Validation of Phantoms Used in Conjunction with Optical Measurement of Tissue V, 85830F (28 February 2013); https://doi.org/10.1117/12.2000834

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