Compact Raman needle probe with fine needle aspiration biopsy for solid tissues

Jianfeng Wang; Wei Zheng; Zhiwei Huang

doi:10.1117/12.2080944

5 March 2015 Compact Raman needle probe with fine needle aspiration biopsy for solid tissues

Jianfeng Wang, Wei Zheng, Zhiwei Huang

Proceedings Volume 9317, Optical Fibers and Sensors for Medical Diagnostics and Treatment Applications XV; 931703 (2015) https://doi.org/10.1117/12.2080944
Event: SPIE BiOS, 2015, San Francisco, California, United States

Abstract

Raman spectroscopy represents a label-free vibrational spectroscopic technique for studying the biochemical and biomolecular compositions of human body. Raman probe is a key component to facilitate the in vivo diagnosis by using Raman spectroscopy. We investigated a compact Raman needle probe design to be integrated into a device that can also take biopsies of solid tissues for cytological assessment, enabling concurrent Raman spectroscopic interrogation and fine needle aspiration biopsy with a single needle penetration. We described the fabrication of the Raman needle probe and its assembly with the biopsy device. Example Raman spectra of various solid tissues are given.

Citation Download Citation

Jianfeng Wang, Wei Zheng, and Zhiwei Huang "Compact Raman needle probe with fine needle aspiration biopsy for solid tissues", Proc. SPIE 9317, Optical Fibers and Sensors for Medical Diagnostics and Treatment Applications XV, 931703 (5 March 2015); https://doi.org/10.1117/12.2080944

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