Azimuthally invariant Mueller-matrix mapping of optically anisotropic layers of biological networks of blood plasma in the diagnosis of liver disease

A. G. Ushenko; A. V. Dubolazov; V. A. Ushenko; Yu. A. Ushenko; M. Yu. Sakhnovskiy; O. Pavlyukovich; N. Pavlyukovich; O. Novakovskaya; M. P. Gorsky

doi:10.1117/12.2237684

14 September 2016 Azimuthally invariant Mueller-matrix mapping of optically anisotropic layers of biological networks of blood plasma in the diagnosis of liver disease

A. G. Ushenko, A. V. Dubolazov, V. A. Ushenko, Yu. A. Ushenko, M. Yu. Sakhnovskiy, O. Pavlyukovich, N. Pavlyukovich, O. Novakovskaya, M. P. Gorsky

Author Affiliations +

Proceedings Volume 9970, Optics and Photonics for Information Processing X; 99701G (2016) https://doi.org/10.1117/12.2237684
Event: SPIE Optical Engineering + Applications, 2016, San Diego, California, United States

Abstract

The model of Mueller-matrix description of mechanisms of optical anisotropy that typical for polycrystalline layers of the histological sections of biological tissues and fluids - optical activity, birefringence, as well as linear and circular dichroism - is suggested. Within the statistical analysis distributions quantities of linear and circular birefringence and dichroism the objective criteria of differentiation of myocardium histological sections (determining the cause of death); films of blood plasma (liver pathology); peritoneal fluid (endometriosis of tissues of women reproductive sphere); urine (kidney disease) were determined. From the point of view of probative medicine the operational characteristics (sensitivity, specificity and accuracy) of the method of Mueller-matrix reconstruction of optical anisotropy parameters were found.

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A. G. Ushenko, A. V. Dubolazov, V. A. Ushenko, Yu. A. Ushenko, M. Yu. Sakhnovskiy, O. Pavlyukovich, N. Pavlyukovich, O. Novakovskaya, and M. P. Gorsky "Azimuthally invariant Mueller-matrix mapping of optically anisotropic layers of biological networks of blood plasma in the diagnosis of liver disease", Proc. SPIE 9970, Optics and Photonics for Information Processing X, 99701G (14 September 2016); https://doi.org/10.1117/12.2237684

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