Using optical coherence tomography (OCT) intraoperatively for pituitary gland and adenoma differentiation, might lead to a more distinct resection of tumor tissue. Therefore, more gland tissue would be preserved and invasively grown adenoma tissue can be detected and removed.
We evaluate the feasibility of laser scanning microscope based OCT for differentiation of healthy and tumor tissue on biopsies resected during surgery. The OCT images are compared to histopathological results. Resolution reduced OCT images are automatically analyzed to estimate the performance parameters for a possible endoscopic translation.
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