Dr. Fabrice Manns Profile

Dr. Fabrice Manns

Professor at University of Miami

SPIE Involvement:

Conference Program Committee | Author | Editor

Publications (71)

Proceedings Article | 13 March 2024 Presentation

Age-dependent analysis of lens Brillouin shift and objective accommodation

Leana Rohman, Justin Schumacher, Marco Ruggeri, Jean-Marie Parel, Giuliano Scarcelli, Kirill Larin, Fabrice Manns

Proceedings Volume PC12824, PC128240P (2024) https://doi.org/10.1117/12.3000756

KEYWORDS: Optical coherence tomography, Objectives, Biomechanics, Analytical research, Eye, Optical microscopy, Microscopy, Microscopes, In vivo imaging, Image processing

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Proceedings Article | 13 March 2024 Presentation

Multimodal elastography to evaluate the in vivo structure-function relationship of lens mechanics in presbyopia

Justin Schumacher, Leana Rohman, Christian Zevallos-Delgado, Marco Ruggeri, Jean-Marie Parel, Fabrice Manns, Kirill Larin, Giuliano Scarcelli

Proceedings Volume PC12824, PC128240Q (2024) https://doi.org/10.1117/12.3001919

KEYWORDS: In vivo imaging, Elastography, Mechanics, Visual process modeling, Microscopy, Eye, Data modeling, Visualization, Visual system, Therapeutics

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Proceedings Article | 13 March 2024 Presentation

Quantification of the centripetal ciliary muscle movement during accommodation with transscleral OCT imaging

Marco Ruggeri, Iulen Cabeza-Gil, Fabrice Manns

Proceedings Volume PC12824, PC128240W (2024) https://doi.org/10.1117/12.3005453

KEYWORDS: Muscles, Optical coherence tomography, Shape analysis, Design and modelling, Crystalline lens, Anatomy

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Proceedings Article | 12 March 2024 Poster + Paper

Assessment of safe acoustic radiation force for crystalline lens optical coherence elastography in ex-vivo porcine eyes

Christian Zevallos-Delgado, Taye Mekonnen, Manmohan Singh, Justin Schumacher, Giuliano Scarcelli, Leana Rohman, Fabrice Manns, Salavat Aglyamov, Kirill Larin

Proceedings Volume 12844, 128440D (2024) https://doi.org/10.1117/12.3002520

KEYWORDS: Acoustics, Crystalline lens, Optical coherence tomography, Elastography, Tissues, Optical coherence, Confocal microscopy, Wave propagation, Ultrasound transducers, Safety

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Proceedings Article | 17 March 2023 Presentation

Combining OCE and Brillouin microscopy to evaluate in vivo lens biomechanics in 3D

Justin Schumacher, Alexander Schill, Manmohan Singh, Fabrice Manns, Kirill Larin, Giuliano Scarcelli

Proceedings Volume PC12360, PC123600N (2023) https://doi.org/10.1117/12.2649355

KEYWORDS: Microscopy, In vivo imaging, Therapeutics, Human subjects, Glasses, Eyeglasses, Eye, Elastography, Coherence (optics)

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Proceedings Article | 4 March 2022 Presentation + Paper

Measurements of mechanical steady-state accommodation fluctuations using optical coherence tomography

Leana Rohman, Marco Ruggeri, Yu-Cherng Chang, Alex Gonzalez, Arthur Ho, Jean-Marie Parel, Fabrice Manns

Proceedings Volume 11941, 1194107 (2022) https://doi.org/10.1117/12.2608274

KEYWORDS: Eye, Optical coherence tomography, Heart, Ultrasonography, Image segmentation, Vitreous, Software development, Refractive index, Oximeters, Optical switching, Lenses

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Proceedings Article | 5 March 2021 Presentation

High speed biometry of the crystalline lens during accommodation with swept source OCT

Marco Ruggeri, Yu-Cherng Chang, Gabrielle Monterano Mesquita, Giulia Belloni, Siobhan Williams, Arthur Ho, Jean-Marie Parel, Fabrice Manns

Proceedings Volume 11623, 116230P (2021) https://doi.org/10.1117/12.2582794

KEYWORDS: Crystals, Optical coherence tomography, Mechanics, Imaging systems, Image segmentation, High speed imaging, Crystallography

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Proceedings Article | 13 March 2019 Presentation

Spherical aberration of the crystalline lens measured in-vitro using an LRT-OCT system (Conference Presentation)

Siobhan Williams, Marco Ruggeri, Bianca Heilman, Yu-Cherng Chang, Ashik Mohamed, Geetha Sravani, Cornelis Rowaan, Alex Gonzalez, Arthur Ho, Jean-Marie Parel, Fabrice Manns

Proceedings Volume 10858, 108580G (2019) https://doi.org/10.1117/12.2508664

KEYWORDS: Monochromatic aberrations, Crystals, In vitro testing, Software development, Geometrical optics, Biometrics, 3D image processing, Optical coherence tomography, Raster graphics, Tissues

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Proceedings Article | 14 March 2018 Presentation

Objective dynamic changes in lens curvature during accommodation using optical coherence tomography images (Conference Presentation)

Siobhan Williams, Giovanni Gregori, Marco Ruggeri, Yu-Cherng Chang, Florence Cabot, Arthur Ho, Sonia Yoo, Jean-Marie Parel, Fabrice Manns

Proceedings Volume 10474, 1047419 (2018) https://doi.org/10.1117/12.2295005

KEYWORDS: Optical coherence tomography, Calibration, Optical spheres, In vivo imaging, Visualization, Detection and tracking algorithms, Image analysis

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Proceedings Article | 16 May 2017 Presentation

Combined laser-ray tracing and OCT system for biometry of the crystalline lens (Conference Presentation)

Marco Ruggeri, Bianca Maceo Heilman, Yue Yao, Yu-Cherng Chang, Alex Gonzalez, Cornelis Rowaan, Ashik Mohamed, Siobhan Williams, Heather Durkee, Juan Silgado, Andres Bernal, Esdras Arrieta-Quintero, Arthur Ho, Jean-Marie Parel, Fabrice Manns

Proceedings Volume 10045, 100451F (2017) https://doi.org/10.1117/12.2256235

KEYWORDS: Biophysics, Holmium, Optical coherence tomography, Crystals, Laser crystals, Eye, Refractive index, Imaging systems, Laser development, Refractor telescopes

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Proceedings Article | 16 May 2017 Presentation

Synchronous imaging of the pulse response of the ciliary muscle and lens with SD-OCT (Conference Presentation)

Yu-Cherng Chang, Alex Pham, Siobhan Williams, Karam Alawa, Carolina de Freitas, Marco Ruggeri, Jean-Marie Parel, Fabrice Manns

Proceedings Volume 10045, 100451G (2017) https://doi.org/10.1117/12.2256323

KEYWORDS: Biophysics, Eye, Image segmentation, Imaging systems, Optical coherence tomography, Cornea, Distortion, Refraction, Optical testing, Biometrics

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Proceedings Article | 26 April 2016 Presentation

Simultaneous refraction measurement and OCT axial biometry of the eye during accommodation (Conference Presentation)

Carolina De Freitas, Victor Hernandez, Marco Ruggeri, Heather Durkee, Siobhan Williams, Giovanni Gregori, Arthur Ho, Fabrice Manns, Jean-Marie Parel

Proceedings Volume 9693, 969315 (2016) https://doi.org/10.1117/12.2218145

KEYWORDS: Refraction, Optical coherence tomography, Eye, Wavefront sensors, Holmium, Biometrics, Optical alignment, Data acquisition, Optical spheres, Optical switching

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Proceedings Article | 26 April 2016 Presentation

Simultaneous hand-held contact color fundus and SD-OCT imaging for pediatric retinal diseases (Conference Presentation)

Marco Ruggeri, Victor Hernandez, Carolina De Freitas, Nidhi Relhan, Juan Silgado, Fabrice Manns, Jean-Marie Parel

Proceedings Volume 9693, 969309 (2016) https://doi.org/10.1117/12.2218172

KEYWORDS: Optical coherence tomography, Imaging systems, Retinal scanning, Photography, Retina, Eye, Ophthalmoscopy, Digital cameras, Cameras, Diagnostics

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Proceedings Article | 12 March 2015 Paper

Co-focused ultrasound and optical coherence elastography system for the study of age-related changes of biomechanical properties of crystalline lens in rabbit eyes

Chen Wu, Zhaolong Han, Shang Wang, Jiasong Li, Manmohan Singh, Chih-hao Liu, Salavat Aglyamov, Stanislav Emelianov, Fabrice Manns, Kirill Larin

Proceedings Volume 9307, 930716 (2015) https://doi.org/10.1117/12.2079532

KEYWORDS: Ultrasonography, Crystals, Optical coherence tomography, Acoustics, Elastography, Eye, Crystallography, Coherence (optics), Transducers, Tissues

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Proceedings Article | 12 March 2015 Paper

Determining the optomechanical properties of accommodating gel for lens refilling surgery using finite element analysis and numerical ray-tracing

Hooman Mohammad-Pour, Sangarapillai Kanapathipillai, Fabrice Manns, Arthur Ho

Proceedings Volume 9307, 930715 (2015) https://doi.org/10.1117/12.2076093

KEYWORDS: Geometrical optics, Ions, Finite element methods, Data modeling, Crystals, Refractive index, Surgery, Mechanics, Protactinium, Amplifiers

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Proceedings Article | 4 March 2014 Paper

Combining optical coherence tomography with acoustic radiation force for depth-dependent biomechanics of crystalline lens

Shang Wang, Salavat Aglyamov, Andrei Karpiouk, Jiasong Li, Stanislav Emelianov, Fabrice Manns, Kirill Larin

Proceedings Volume 8934, 89340Y (2014) https://doi.org/10.1117/12.2041976

KEYWORDS: Crystals, Optical coherence tomography, Natural surfaces, Biomedical optics, Tissues, Tissue optics, Acoustics, Elastography, Ultrasonography, Eye

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Proceedings Article | 28 February 2014 Paper

Biometry of the ciliary muscle during dynamic accommodation assessed with OCT

Marco Ruggeri, Victor Hernandez, Carolina de Freitas, Fabrice Manns, Jean-Marie Parel

Proceedings Volume 8930, 89300W (2014) https://doi.org/10.1117/12.2044309

KEYWORDS: Optical coherence tomography, Eye, Imaging systems, Image segmentation, Refractive index, Sclera, Algorithm development, 3D image processing, Ray tracing, Image processing

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Proceedings Article | 28 February 2014 Paper

Finite element study on the effects of GRIN order on the accommodative response of the human crystalline lens

Hooman Mohammad-Pour, Sangarapillai Kanapathipillai, Fabrice Manns, Arthur Ho

Proceedings Volume 8930, 89300R (2014) https://doi.org/10.1117/12.2044430

KEYWORDS: GRIN lenses, Refractive index, Crystals, Data modeling, Crystallography, Geometrical optics, Optical components, Eye, Numerical analysis, Computing systems

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Proceedings Article | 3 March 2010 Paper

Small animal ocular biometry using optical coherence tomography

Marco Ruggeri, Omer Kocaoglu, Stephen Uhlhorn, David Borja, Raksha Urs, Tsung-Han Chou, Vittorio Porciatti, Jean-Marie Parel, Fabrice Manns

Proceedings Volume 7550, 755016 (2010) https://doi.org/10.1117/12.846937

KEYWORDS: Optical coherence tomography, Eye, Cornea, Refractive index, Image segmentation, Interfaces, Refraction, In vivo imaging, Biometrics, Ray tracing

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Proceedings Article | 18 April 2005 Paper

Noncontact optical measurement of lens capsule thickness during simulated accommodation

Noel Ziebarth, Fabrice Manns, Carolina Acosta, Jean-Marie Parel

Proceedings Volume 5688, (2005) https://doi.org/10.1117/12.597648

KEYWORDS: Eye, Fiber couplers, Optical testing, Actuators, Refractive index, Tissue optics, Tissues, Natural surfaces, Aspheric lenses, Optical design

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Purpose: To non-invasively measure the thickness of the anterior and posterior lens capsule, and to determine if it significantly changes during accommodation. Methods: Anterior and posterior capsule thickness was measured on post-mortem lenses using a non-contact optical system using a focus-detection technique. The optical system uses a 670nm laser beam delivered to a single-mode fiber coupler. The output of the fiber coupler is focused on the tissue surface using an aspheric lens (NA=0.68) mounted on a translation stage with a motorized actuator. Light reflected from the sample surface is collected by the fiber coupler and sent to a photoreceiver connected to a computer-controlled data acquisition system. Optical intensity peaks are detected when the aspheric lens is focused on the capsule boundaries. The capsule thickness is equal to the distance traveled between two peaks multiplied by the capsule refractive index. Anterior and posterior lens capsule thickness measurements were performed on 18 cynomolgus (age average: 6±1 years, range: 4-7 years) eyes, 1 rhesus (age: 2 years) eye, and 12 human (age average: 65±16, range: 47-92) eyes during simulated accommodation. The mounted sample was placed under the focusing objective of the optical system so that the light was incident on the center pole. Measurements were taken of the anterior lens capsule in the unstretched and the stretched 5mm states. The lens was flipped, and the same procedure was performed for the posterior lens capsule. Results: The precision of the optical system was determined to be ±0.5um. The resolution is 4um and the sensitivity is 52dB. The human anterior lens capsule thickness was 6.0±1.2um unstretched and 4.9±0.9um stretched (p=0.008). The human posterior lens capsule was 5.7±1.2um unstretched and 5.7±1.4um stretched (p=0.974). The monkey anterior lens capsule thickness was 5.9±1.9um unstretched and 4.8±1.0um stretched (p=0.002). The monkey posterior lens capsule was 5.9±2.0um unstretched and 5.1±1.3um stretched (p=0.128). Conclusions: The results indicate that the primate anterior lens capsule thickness changes during accommodation.

Proceedings Article | 18 April 2005 Paper

Ex-vivo crystalline lens optical quality measurements during simulated accommodation using a single pass PSF measurement system

David Borja, Gaku Takeuchi, Katsuhiko Kobayashi, Fabrice Manns, Jean Marie Parel

Proceedings Volume 5688, (2005) https://doi.org/10.1117/12.600618

KEYWORDS: Modulation transfer functions, Point spread functions, Crystals, Quality measurement, Sclera, Relays, Optical testing, Spatial frequencies, Crystal optics, Optical transfer functions

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Proceedings Article | 13 July 2004 Paper

Noncontact optical measurement of lens capsule thickness ex vivo

Noel Ziebarth, Fabrice Manns, Stephen Uhlhorn, Jean-Marie Parel

Proceedings Volume 5314, (2004) https://doi.org/10.1117/12.538655

KEYWORDS: Optical testing, Eye, Signal detection, Refractive index, Fiber couplers, Aspheric lenses, Objectives, Optical design, Power meters, Tissues

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Proceedings Article | 13 July 2004 Paper

Effect of the internal optics on the outcome of custom-LASIK in an eye model

Fabrice Manns, Arthur Ho, Jean-Marie Parel

Proceedings Volume 5314, (2004) https://doi.org/10.1117/12.540883

KEYWORDS: Monochromatic aberrations, Eye models, Eye, Cornea, Surgery, Wavefront aberrations, Wavefronts, 3D modeling, OSLO, Biomedical optics

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Proceedings Article | 13 July 2004 Paper

Kinetics of corneal thermal shrinkage

David Borja, Fabrice Manns, William Lee, Jean-Marie Parel

Proceedings Volume 5314, (2004) https://doi.org/10.1117/12.540880

KEYWORDS: Tissues, Temperature metrology, Collagen, Eye, Cornea, Statistical analysis, Data modeling, Sensors, Data analysis, Thermal modeling

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Proceedings Article | 13 July 2004 Paper

Modelling the performance of accommodating intraocular lenses

Arthur Ho, Fabrice Manns, Therese Pham, Simon Evans, Jean-Marie Parel

Proceedings Volume 5314, (2004) https://doi.org/10.1117/12.540879

KEYWORDS: Eye models, Eye, Optical components, Cornea, Modeling, Performance modeling, Retina, Intraocular lenses, Crystals, Vitreous

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Proceedings Article | 12 September 2003 Paper

Predictions of tissue denaturation during experimental laser interstitial thermotherapy for breast tumors

Nelson Salas, Fabrice Manns, Jean-Marie Parel, Peter Milne, David Denham, David Robinson

Proceedings Volume 4949, (2003) https://doi.org/10.1117/12.485165

KEYWORDS: Laser tissue interaction, Fiber lasers, Breast, Tumors, Tissues, Heat therapy, Temperature metrology, Tissue optics, Laser systems engineering, Molybdenum

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Proceedings Article | 12 September 2003 Paper

Microsurgical laser Doppler probe for simultaneous intraoperative monitoring of cochlear blood flow and electrocochleography from the round window

Lidet Abiy, Fred Telischi, Jean-Marie Parel, Fabrice Manns, Ralph Saettele, Krzysztof Morawski, Ozcan Ozdamar, John Borgos, Rafael Delgado, Edward Miskiel, Erdem Yavuz

Proceedings Volume 4949, (2003) https://doi.org/10.1117/12.476428

KEYWORDS: Blood circulation, Electrodes, Doppler effect, Laser beam diagnostics, Prototyping, Ear, Nerve, Surgery, In vivo imaging, Intelligence systems

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Proceedings Article | 14 July 2003 Paper

Laser-induced photochemical surface modification of PMMA for fibrin-free intraocular lens

Yuji Sato, Katsuya Tanizawa, Fabrice Manns, Jean-Marie Parel, Masataka Murahara

Proceedings Volume 4951, (2003) https://doi.org/10.1117/12.477993

KEYWORDS: Polymethylmethacrylate, Lamps, Excimer lasers, Excimers, Natural surfaces, Proteins, Fluorine, Absorption, Transmittance, Tissues

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Proceedings Article | 14 July 2003 Paper

Effects of immersion solutions on corneal tissue strip hydration and thermal shrinkage

David Borja, Fabrice Manns, Peggy Lamar, Alexander Rosen, Jean-Marie Parel

Proceedings Volume 4951, (2003) https://doi.org/10.1117/12.482368

KEYWORDS: Tissues, Cornea, Tissue optics, Temperature metrology, Eye, Thermal effects, Ultrasonography, Laser tissue interaction, Process control, Photography

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Proceedings Article | 14 July 2003 Paper

Assessing changes in physical lens dimensions during immersion in tissue preservation media using shadowphotogrammetry

Alexander Rosen, David Denham, Fabrice Manns, Viviana Fernandez, Joseph Stoiber, Robert Augusteyn, Jean-Marie Parel

Proceedings Volume 4951, (2003) https://doi.org/10.1117/12.482374

KEYWORDS: Tissues, Eye, Liquids, Digital imaging, Crystals, Vitreous, Digital photography, Visualization, Profiling, Control systems

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Proceedings Article | 14 July 2003 Paper

Corneal ablation rate at 266 nm

Per Soderberg, Fabrice Manns, Stephen Sulhorn, Nelson Salas, Peggy Lamar, Jean-Marie Parel

Proceedings Volume 4951, (2003) https://doi.org/10.1117/12.482465

KEYWORDS: Cornea, Laser ablation, Scanning electron microscopy, Eye, Microscopes, Solid state lasers, Tissues, Vitreous, Clocks, Calibration

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Proceedings Article | 14 July 2003 Paper

Qualitative optical-thermal model of argon, selective, and microsecond infrared laser trabeculoplasty

Fabrice Manns, Jean-Marie Parel, Viviana Fernandez, Joseph Stoiber, Peggy Lamar, Nelson Salas, Francisco Fantes

Proceedings Volume 4951, (2003) https://doi.org/10.1117/12.482372

KEYWORDS: Diffusion, Thermal modeling, Absorption, Argon ion lasers, Laser optics, Tissue optics, Infrared lasers, Laser scattering, Continuous wave operation, Nd:YAG lasers

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SPIE Journal Paper | 1 April 2003 Open Access

Semianalytical thermal model for subablative laser heating of homogeneous nonperfused biological tissue: application to laser thermokeratoplasty

Fabrice Manns, David Borja, Jean-Marie Parel, William Smiddy, William Culbertson

JBO, Vol. 8, Issue 02, (April 2003) https://doi.org/10.1117/12.10.1117/1.1560644

KEYWORDS: Tissues, Convection, Cornea, Laser tissue interaction, Thermal modeling, Pulsed laser operation, Absorption, Collimation, Laser irradiation, Scattering

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Proceedings Article | 17 June 2002 Paper

Experimental laser interstitial thermotherapy in ex-vivo porcine tissue at 940 nm

Nelson Salas, Fabrice Manns, Jean-Marie Parel, Peter Milne, Manuel Figueroa, David Denham, David Robinson

Proceedings Volume 4609, (2002) https://doi.org/10.1117/12.438871

KEYWORDS: Heat therapy, Laser tissue interaction, Laser therapeutics, Laser vision correction, Surgery, Calcium

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Proceedings Article | 13 June 2002 Paper

Anterior ciliary sclerotomy: effect on corneal topography, globe integrity, and the role of a novel antifibrotic gel

Peggy Lamar, Viviana Fernandez, Fabrice Manns, Sander Dubovy, Stanley Zipper, Samith Sandadi, Natsushi Nakagawa, Marc Weiser, Francois Malecaze, Jean-Marie Parel

Proceedings Volume 4611, (2002) https://doi.org/10.1117/12.470603

KEYWORDS: Quantum wells, Eye, Holmium, Earth Viewing Camera, Safety, Sodium, Vitreous, Sclera, Diamond, Surgery

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Proceedings Article | 13 June 2002 Paper

Synthetic cornea: biocompatibility and optics

Jean-Marie Parel, Stefan Kaminski, Viviana Fernandez, E. Alfonso, Peggy Lamar, Emmanuel Lacombe, Bernard Duchesne, Sander Dubovy, Fabrice Manns, Pascal Rol

Proceedings Volume 4611, (2002) https://doi.org/10.1117/12.470584

KEYWORDS: Cornea, Tissues, Polymethylmethacrylate, Polymers, Surgery, Eye, Tissue optics, Natural surfaces, Excimer lasers, Animal model studies

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Purpose. Experimentally find a method to provide a safe surgical technique and an inexpensive and long lasting mesoplant for the restoration of vision in patients with bilateral corneal blindness due to ocular surface and stromal diseases. Methods. Identify the least invasive and the safest surgical technique for synthetic cornea implantation. Identify the most compatible biomaterials and the optimal shape a synthetic cornea must have to last a long time when implanted in vivo. Results. Penetrating procedures were deemed too invasive, time consuming, difficult and prone to long term complications. Therefore a non-penetrating delamination technique with central trephination was developed to preserve the integrity of Descemet's membrane and the anterior segment. Even though this approach limits the number of indications, it is acceptable since the majority of patients only have opacities in the stroma. The prosthesis was designed to fit in the removed tissue plane with its skirt fitted under the delaminated stroma. To improve retention, the trephination wall was made conical with the smallest opening on the anterior surface and a hat-shaped mesoplant was made to fit. The skirt was perforated in its perimeter to allow passage of nutrients and tissues ingrowths. To simplify the fabrication procedure, the haptic and optic were made of the same polymer. The intrastromal biocompatibility of several hydrogels was found superior to current clinically used PMMA and PTFE materials. Monobloc mesoplants made of 4 different materials were implanted in rabbits and followed weekly until extrusion occurred. Some remained optically clear allowing for fundus photography. Conclusions. Hydrogel synthetic corneas can be made to survive for periods longer than 1 year. ArF excimer laser photoablation studies are needed to determine the refractive correction potential of these mesoplants. A pilot FDA clinical trial is needed to assess the mesoplant efficacy and very long-term stability.

Proceedings Article | 13 June 2002 Paper

Calculation of corneal temperature and shrikage during laser thermokeratoplasty (LTK)

Fabrice Manns, David Borja, Jean-Marie Parel

Proceedings Volume 4611, (2002) https://doi.org/10.1117/12.470581

KEYWORDS: Thermal modeling, Cornea, Pulsed laser operation, Laser tissue interaction, Collagen, Tissues, Laser irradiation, Thermography, Laser vision correction, Data modeling

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Proceedings Article | 13 June 2002 Paper

Thermoelectrically controlled device for studies of temperature-induced corneal shrinkage

David Borja, Fabrice Manns, Viviana Fernandez, Peggy Lamar, Per Soederberg, Jean-Marie Parel

Proceedings Volume 4611, (2002) https://doi.org/10.1117/12.470583

KEYWORDS: Tissues, Cornea, Sensors, Temperature metrology, Calibration, Thermoelectric materials, Copper, Eye, Computing systems, Data acquisition

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Proceedings Article | 7 June 2001 Paper

Feasibility of simultaneous correction of ametropia by varying gel refractive index with phaco-ersatz

Arthur Ho, Paul Erickson, Fabrice Manns, Therese Pham, Jean-Marie Parel

Proceedings Volume 4245, (2001) https://doi.org/10.1117/12.429263

KEYWORDS: Refractive index, Eye models, Polymers, Photorefractive polymers, Eye, Crystals, Ray tracing, Cornea, Aspheric lenses, Spherical lenses

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Proceedings Article | 7 June 2001 Paper

Corneal modeling using conic section fits of PAR corneal topography system measurements

Stanley Zipper, Fabrice Manns, Viviana Fernandez, Samith Sandadi, Arthur Ho, Jean-Marie Parel

Proceedings Volume 4245, (2001) https://doi.org/10.1117/12.429261

KEYWORDS: Cornea, Eye, Eye models, Microscopes, MATLAB, Optical spheres, Medical research, Shape analysis, Monochromatic aberrations, Systems modeling

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Proceedings Article | 7 June 2001 Paper

Calculation of the primary spherical aberration of an eye model using paraxial ray tracing with matrix optics

Fabrice Manns, Arthur Ho, Jean-Marie Parel

Proceedings Volume 4245, (2001) https://doi.org/10.1117/12.429290

KEYWORDS: Eye, Eye models, Monochromatic aberrations, Cornea, LASIK, Optical matrix switches, Surgery, Laser vision correction, Spherical lenses, Refraction

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Proceedings Article | 7 June 2001 Paper

Measurement of the topography of human cadaver lenses using the PAR corneal topography system

Viviana Fernandez, Fabrice Manns, Stanley Zipper, Samith Sandadi, Marie Hamaoui, Hassan Tahi, Arthur Ho, Jean-Marie Parel

Proceedings Volume 4245, (2001) https://doi.org/10.1117/12.429262

KEYWORDS: Eye, Lenses, Crystals, Eye models, Cornea, Microscopes, Natural surfaces, Polymers, Ophthalmology, Medical research

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Proceedings Article | 21 May 2001 Paper

Experimental laser interstitial thermotherapy in ex-vivo porcine tissue at 980 nm and 830 nm

Nelson Salas, Fabrice Manns, Jean-Marie Parel, Peter Milne, Ahmed Minhaj, David Denham, David Robinson

Proceedings Volume 4244, (2001) https://doi.org/10.1117/12.427842

KEYWORDS: Tissues, Laser tissue interaction, Laser systems engineering, Semiconductor lasers, Breast, Temperature metrology, Heat therapy, Tissue optics, Tumors, Optical fibers

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Proceedings Article | 21 May 2001 Paper

X-ray monitoring of laser interstitial thermotherapy (LITT) in ex-vivo porcine tissue

Ahmed Minhaj, Fabrice Manns, Peter Milne, David Denham, Nelson Salas, Jean-Marie Parel, David Robinson

Proceedings Volume 4244, (2001) https://doi.org/10.1117/12.427841

KEYWORDS: Tissues, X-rays, X-ray imaging, Laser tissue interaction, Laser irradiation, Imaging systems, X-ray lasers, Heat therapy, Optical fibers, Temperature metrology

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Proceedings Article | 7 June 2000 Paper

Intraocular implants for the surgical correction of presbyopia

Jean-Marie Parel, Pascal Rol, Hassan Tahi, Fabrice Manns, Peter Milne, Marie Hamaoui, Arthur Ho, Brien Holden

Proceedings Volume 3908, (2000) https://doi.org/10.1117/12.387514

KEYWORDS: Eye, Polymers, Crystals, Surgery, Cornea, Intraocular lenses, Clinical trials, Tissues, Monochromatic aberrations, Visualization

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Proceedings Article | 7 June 2000 Paper

Ex-vivo testing of crystalline lens substitutes: a pilot study

Marie Hamaoui, Jean-Marie Parel, Fabrice Manns, Hassan Tahi, Arthur Ho, Brien Holden

Proceedings Volume 3908, (2000) https://doi.org/10.1117/12.387515

KEYWORDS: Eye, Polymers, Crystals, In vivo imaging, Cornea, Microscopes, Eye models, Surgery, Photography, Vitreous

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Proceedings Article | 7 June 2000 Paper

Assessment of changes in corneal shape as a function of intraocular pressure: a pilot study

Kira Brenman, Hassan Tahi, Fabrice Manns, Bernard Duchesne, Jean-Marie Parel, Emmanuel Lacombe

Proceedings Volume 3908, (2000) https://doi.org/10.1117/12.387513

KEYWORDS: Eye, Cornea, Statistical analysis, Vitreous, Natural surfaces, Transplantation, Refractor telescopes, Tissues, Sensors, Biophysics

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Proceedings Article | 17 May 2000 Paper

Development of a tissue phantom for experimental studies on laser interstitial thermotherapy of breast cancer

Nelson Salas, Fabrice Manns, Pascal Chapon, Peter Milne, Sergio Mendoza, David Denham, Jean-Marie Parel, David Robinson

Proceedings Volume 3907, (2000) https://doi.org/10.1117/12.386232

KEYWORDS: Absorption, Laser tissue interaction, Heat therapy, Laser irradiation, Tissues, Breast cancer, Temperature metrology, Breast, Tumors, Tissue optics

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Proceedings Article | 22 June 1999 Paper

Mathematical analysis of the temperature field during ex-vivo and in-vivo experimental laser interstitial thermotherapy (LITT) in breast tissue models

Fabrice Manns, Peter Milne, Nelson Salas, Nish Pandya, David Denham, Jean-Marie Parel, David Robinson

Proceedings Volume 3590, (1999) https://doi.org/10.1117/12.351000

KEYWORDS: Temperature metrology, Tissues, Laser tissue interaction, In vivo imaging, Semiconductor lasers, Laser irradiation, Breast cancer, Laser beam diagnostics, Heat therapy, Continuous wave operation

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Proceedings Article | 22 June 1999 Paper

Developing clinical trials for breast cancer interstitial therapy

David Robinson, Jean-Marie Parel, Peter Milne, Fabrice Manns, David Denham

Proceedings Volume 3590, (1999) https://doi.org/10.1117/12.351006

KEYWORDS: Cancer, Clinical trials, Breast cancer, Laser therapeutics, Tumors, Tissues, Breast, Mammography, Ultrasonography, Oncology

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Proceedings Article | 22 June 1999 Paper

In-situ measurement and analysis of the temperature fields in laser interstitial thermotherapy of breast cancer

Peter Milne, Fabrice Manns, David Denham, Jean-Marie Parel, David Robinson

Proceedings Volume 3590, (1999) https://doi.org/10.1117/12.351001

KEYWORDS: Tissues, Breast, Temperature metrology, Breast cancer, Tissue optics, Heat therapy, In vivo imaging, Fiber optics, Fiber lasers, Laser therapeutics

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Proceedings Article | 18 June 1999 Paper

Analysis of eye models for the development of observation contact lenses

Pascal Rol, Fabrice Manns, Jean-Marie Parel, Franz Fankhauser, Peter Niederer

Proceedings Volume 3591, (1999) https://doi.org/10.1117/12.350562

KEYWORDS: Glasses, Monochromatic aberrations, Cornea, Eye models, Mirrors, Refractive index, Eye, Cones, Contact lenses, Data modeling

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Proceedings Article | 18 June 1999 Paper

Scanning photorefractive keratectomy at 213 nm: PMMA ablations

Fabrice Manns, Pascal Rol, Martin Wosnitza, Patrick Maine, Jean-Marie Parel

Proceedings Volume 3591, (1999) https://doi.org/10.1117/12.350577

KEYWORDS: Laser ablation, Polymethylmethacrylate, Optical testing, Cornea, Nd:YAG lasers, Laser beam diagnostics, Near field optics, Pulsed laser operation, Beam shaping, Near field

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Proceedings Article | 1 June 1998 Paper

Spot diameters for scanning photorefractive keratectomy: a comparative study

Fabrice Manns, Jean-Marie Parel

Proceedings Volume 3246, (1998) https://doi.org/10.1117/12.309420

KEYWORDS: Monochromatic aberrations, Surgery, Cornea, Laser ablation, Laser vision correction, Computer simulations, Laser therapeutics, Refractor telescopes, Eye, Algorithm development

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Proceedings Article | 1 June 1998 Paper

Corneal group refractive index measurement using low-coherence interferometry

Stephen Uhlhorn, Fabrice Manns, Hassan Tahi, Pascal Rol, Jean-Marie Parel

Proceedings Volume 3246, (1998) https://doi.org/10.1117/12.309424

KEYWORDS: Refractive index, Cornea, Mirrors, Interferometers, Optical testing, Reflection, Geometrical optics, Interferometry, Eye, In vitro testing

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Proceedings Article | 1 June 1998 Paper

Scleral indentation height after laser scleral buckling

Se Kang, Jean-Marie Parel, Fabrice Manns, Jawheung Lee, William Smiddy

Proceedings Volume 3246, (1998) https://doi.org/10.1117/12.309426

KEYWORDS: Eye, Direct methods, Pulsed laser operation, Medicine, Laser beam diagnostics, Laser vision correction, Ophthalmology, Sclera, Silicon, Laser energy

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Proceedings Article | 26 May 1997 Paper

Optical comparison of multizone and single-zone photorefractive keratectomy

Xochitl Gonzalez-Cirre, Fabrice Manns, Pascal Rol, Jean-Marie Parel

Proceedings Volume 2971, (1997) https://doi.org/10.1117/12.275115

KEYWORDS: Point spread functions, Computer aided design, Eye models, Eye, Image quality, Cornea, Retina, Electroluminescence, Tissues, Computer aided diagnosis and therapy

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Proceedings Article | 26 May 1997 Paper

Scleral heating with pulsed midinfrared lasers and temperature-dependent absorption coefficient

Fabrice Manns, Jean-Marie Parel

Proceedings Volume 2971, (1997) https://doi.org/10.1117/12.275124

KEYWORDS: Absorption, Thermal modeling, Pulsed laser operation, Temperature metrology, Eye models, Diffusion, Sclera, Tissues, Laser tissue interaction, Mid-IR

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Proceedings Article | 22 May 1997 Paper

Update of laser hyperthermic treatment for primary breast cancer: ex-vivo and in-vivo models

David Robinson, Jean-Marie Parel, Xochitl Gonzalez-Cirre, David Denham, Fabrice Manns, Peter Milne, Robert Schachner, Alan Herron, Jason Comander, Gerhard Hauptmann

Proceedings Volume 2970, (1997) https://doi.org/10.1117/12.275021

KEYWORDS: Breast cancer, Animal model studies, Tumor growth modeling, Laser therapeutics, Distortion, Tissues, Instrument modeling, Clinical trials

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