This course introduces attendees to select open-source efforts in the field of medical image analysis. Opportunities for users and developers are presented. The course particularly focuses on the open-source Insight Toolkit (ITK) for medical image segmentation and registration. The course describes the procedure for downloading and installing the toolkit and covers the use of its data representation and filtering classes. Attendees are shown how ITK can be used in their research, rapid prototyping, and application development. COURSE SCHEDULE: Stephen Aylward, Kitware, Inc. – Chapel Hill Office • The Insight Software Consortium: contributing and using open-source • The architecture and installation of the Insight Toolkit Josh Cates, Univ. of Utah • Segmentation methods of the Insight Toolkit Lydia Ng, Allen Brain Institute • Registration methods of the Insight Toolkit Julien Jomier, Kitware, Inc. – Chapel Hill Office • Image IO using the Insight Toolkit • The Image-Guided Surgery Toolkit (http://www.igstk.org) Stephen Aylward, Kitware, Inc. – Chapel Hill Office • Applications of the Insight Toolkit