Recent advances in medical research hypothesize that certain body
fat, in addition to having a classical role of energy storage, may
also have mechanical function. In particular, we analyzed the
infrapatellar fat pad of Hoffa using 3D CT images of the knee at
multiple angles to determine how the fat pad changes shape as the
knee bends and whether the fat pad provides cushioning in the knee
joint. The images were initially processed using a median filter
then segmented using a region growing technique to isolate the fat
pad from the rest of the knee. Next, rigid registration was
performed to align the series of images to match the reference
image. Finally, multi-resolution FEM registration was completed
between the aligned images. The resulting displacements fields
were used to determine the local volume change of the fat pad as
the knee bends from extension to flexion through different angles.
This multi-angle analysis provides a finer description of the
intermediate deformations compared to earlier work, where only a
pair of images (full extension and flexion) was analyzed.
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