Current cervical screening techniques are fairly effective at assessing the ectocervical surface, but they are limited in their capacity to assess the endocervical canal. There is a need for tools that examine the endocervical canal for cancerous or pre-cancerous lesions. This pilot study explores whether an endoscopic imaging approach combining structural and functional imaging techniques (optical coherence tomography (OCT) and autofluorescence imaging (AFI) respectively) can visualize cancerous or pre-cancerous changes in the endocervical canal. We present findings from an on-going in vivo imaging study including sample cases demonstrating precancers and cancers and preliminary features of interest.
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