Protein detection plays an important role in the medical research. Liquid crystals (LCs), as a class of sensitive materials, exhibit a promising ability in the biosensing field. Herein, we exploited an ultrasensitive biosensor for protein detection, employing the whispering-gallery-mode (WGM) from the LC-amplified optofluidic micro-resonator. The biomolecules can trigger both light-matter interactions and the orientation transitions of LC molecules. The WGM spectral wavelength shift was recorded as the sensing indicator, and a detection limit of 15 fM for bovine serum albumin (BSA) was achieved. Our LC-amplified optofluidic biosensor provides a new solution for the ultrasensitive, real-time, and stable biological detection.
Access to the requested content is limited to institutions that have purchased or subscribe to SPIE eBooks.
You are receiving this notice because your organization may not have SPIE eBooks access.*
*Shibboleth/Open Athens users─please
sign in
to access your institution's subscriptions.
To obtain this item, you may purchase the complete book in print or electronic format on
SPIE.org.
INSTITUTIONAL Select your institution to access the SPIE Digital Library.
PERSONAL Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.