Dr. Rebekah Drezek Profile

Dr. Rebekah Drezek

Professor of Bioengineering at Rice Univ

SPIE Involvement:

Author

Publications (33)

Proceedings Article | 13 March 2013 Paper

Multi-system comparison of optical coherence tomography performance with point spread function phantoms

Joshua Pfefer, Anthony Fouad, Chao-Wei Chen, Wei Gong, Peter Tomlins, Peter Woolliams, Rebekah Drezek, Anant Agrawal, Yu Chen

Proceedings Volume 8573, 85730C (2013) https://doi.org/10.1117/12.2007005

KEYWORDS: Point spread functions, Optical coherence tomography, Particles, Silica, Spatial resolution, Gold, Image quality standards, Optical resolution, Image quality, Backscatter

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SPIE Journal Paper | 1 July 2010 Open Access

Quantitative tool for rapid disease mapping using optical coherence tomography images of azoxymethane-treated mouse colon

Amy Winkler, Photini Rice, Rebekah Drezek, Jennifer Barton

JBO, Vol. 15, Issue 04, 041512, (July 2010) https://doi.org/10.1117/12.10.1117/1.3446674

KEYWORDS: Optical coherence tomography, Colon, Tissues, Signal attenuation, Bragg cells, Scattering, Gold, Natural surfaces, In vivo imaging, Image segmentation

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SPIE Journal Paper | 1 July 2010 Open Access

Needle-compatible single fiber bundle image guide reflectance endoscope

Jiantang Sun, Chenghao Shu, Benjamin Appiah, Rebekah Drezek

JBO, Vol. 15, Issue 04, 040502, (July 2010) https://doi.org/10.1117/12.10.1117/1.3465558

KEYWORDS: Reflectivity, Video, Image resolution, Imaging systems, Tissues, Tissue optics, Image processing, Water, Endoscopes, Biopsy

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SPIE Journal Paper | 1 March 2009 Open Access

Guest Editorial: Nanophotonics for Diagnostics, Protection, and Treatment of Cancer and Inflammatory Diseases

Valery Tuchin, Rebekah Drezek, Shuming Nie, Vladimir Zharov

JBO, Vol. 14, Issue 02, 020901, (March 2009) https://doi.org/10.1117/12.10.1117/1.3121424

KEYWORDS: Diagnostics, Cancer, Oncology, Nanophotonics, Imaging spectroscopy, Skin cancer, Nanobiophotonics, Tissues, Particles, Laser scattering

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Proceedings Article | 22 February 2008 Paper

Statistical analysis of FTIR spectra of cervical tissues and diagnostic algorithms for cervical cancer

Benjamin Appiah, Vengadesan Nammalvar, Rebekah Drezek

Proceedings Volume 6863, 68630V (2008) https://doi.org/10.1117/12.764271

KEYWORDS: Tissues, Cancer, Statistical analysis, FT-IR spectroscopy, Cervical cancer, Algorithm development, Infrared spectroscopy, Absorption, Diagnostics, Spectroscopy

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Proceedings Article | 21 February 2008 Paper

Fluorescent and scattering contrast agents in a mouse model of colorectal cancer

Amy Winkler, Photini Rice, Timothy Troutman, Marina Backer, Joseph Backer, Rebekah Drezek, Marek Romanowski, Jennifer Barton

Proceedings Volume 6851, 68510L (2008) https://doi.org/10.1117/12.764043

KEYWORDS: Optical coherence tomography, Colon, Scattering, In vivo imaging, Laser induced fluorescence, Endoscopes, Nanoparticles, Colorectal cancer, Tissues, Nanorods

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SPIE Journal Paper | 1 July 2007 Open Access

Targeting spectral signatures of progressively dysplastic stratified epithelia using angularly variable fiber geometry in reflectance Monte Carlo simulations

Adrien Wang, Vengadesan Nammalvar, Rebekah Drezek

JBO, Vol. 12, Issue 04, 044012, (July 2007) https://doi.org/10.1117/12.10.1117/1.2769328

KEYWORDS: Tissues, Reflectivity, Scattering, Tissue optics, Absorption, Monte Carlo methods, Optical properties, Reflectance spectroscopy, Natural surfaces, Pathology

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SPIE Journal Paper | 1 July 2007 Open Access

Experimental evaluation of angularly variable fiber geometry for targeting depth-resolved reflectance from layered epithelial tissue phantoms

Adrien Wang, Vengadesan Nammalvar, Rebekah Drezek

JBO, Vol. 12, Issue 04, 044011, (July 2007) https://doi.org/10.1117/12.10.1117/1.2769331

KEYWORDS: Reflectivity, Scattering, Tissues, Particles, Tissue optics, Absorption, Anisotropy, Spectroscopy, Optical properties, Structured optical fibers

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SPIE Journal Paper | 1 April 2007

Enhanced gold nanoshell scattering contrast using angled fiber probes

Vengadesan Nammalvar, Adrien Wang, Rebekah Drezek

JNP, Vol. 1, Issue 01, 013510, (April 2007) https://doi.org/10.1117/12.10.1117/1.2741242

KEYWORDS: Tissues, Reflectivity, Scattering, Gold, Tissue optics, Cancer, Absorption, Mie scattering, Signal detection, Reflectance spectroscopy

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Proceedings Article | 14 February 2007 Paper

Experimental evaluation of angularly variable fiber geometry for targeting depth-resolved reflectance from layered epithelial tissue phantoms

Adrien Wang, Vengadesan Nammalvar, Rebekah Drezek

Proceedings Volume 6433, 64330B (2007) https://doi.org/10.1117/12.702005

KEYWORDS: Tissues, Reflectivity, Tissue optics, Absorption, Scattering, Optical properties, Spectroscopy, Reflectance spectroscopy, Photons, Pathology

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Proceedings Article | 10 February 2007 Paper

Enhanced gold nanoshell scattering contrast in cervical tissue using angled fiber probes

Vengadesan Nammalvar, Adrien Wang, Rebekah Drezek

Proceedings Volume 6447, 64470H (2007) https://doi.org/10.1117/12.702910

KEYWORDS: Tissues, Reflectivity, Gold, Scattering, Tissue optics, Cancer, Diffusion, Natural surfaces, Reflectance spectroscopy, Silica

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SPIE Journal Paper | 1 July 2006 Open Access

Quantitative evaluation of optical coherence tomography signal enhancement with gold nanoshells

Anant Agrawal, Stanley Huang, Alex Lin, Min-Ho Lee, Jennifer Barton, Rebekah Drezek, Joshua Pfefer

JBO, Vol. 11, Issue 04, 041121, (July 2006) https://doi.org/10.1117/12.10.1117/1.2339071

KEYWORDS: Optical coherence tomography, Signal attenuation, Gold, Backscatter, Tissues, Scattering, Tumors, Particles, Optical properties, Signal detection

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Proceedings Article | 14 April 2006 Paper

Protease-activated quantum dot probes

Emmanuel Chang, Jiantang Sun, Jordan Miller, William Yu, Vicki Colvin, Jennifer West, Rebekah Drezek

Proceedings Volume 6191, 61911E (2006) https://doi.org/10.1117/12.660485

KEYWORDS: Luminescence, Quantum dots, Gold, Nanoparticles, Energy transfer, Tissue optics, Fluorescence resonance energy transfer, Optical imaging, Signal processing, Quantum optics

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Proceedings Article | 15 February 2006 Paper

Computational modeling of device-tissue interface geometries for time-resolved fluorescence in layered tissue

T. Joshua Pfefer, Anant Agrawal, Rebekah Drezek

Proceedings Volume 6083, 608305 (2006) https://doi.org/10.1117/12.646960

KEYWORDS: Tissues, Luminescence, Monte Carlo methods, Signal detection, Time resolved spectroscopy, Fluorescence spectroscopy, Tissue optics, Optical properties, Computational modeling, Scattering

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Proceedings Article | 18 November 2005 Paper

Modeling and experimental observations of gold nanoshell reflectance

Alex W. Lin, Nastassja Lewinski, Andrey Rakalin, Min-Ho Lee, Naomi Halas, Rebekah Drezek

Proceedings Volume 6010, 60100L (2005) https://doi.org/10.1117/12.633420

KEYWORDS: Gold, Diffuse reflectance spectroscopy, Reflectivity, Monte Carlo methods, Tissue optics, Scattering, Optical properties, Absorption, Backscatter, Nanoparticles

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SPIE Journal Paper | 1 November 2005 Open Access

Optically tunable nanoparticle contrast agents for early cancer detection: model-based analysis of gold nanoshells

Alex Lin, Nastassja Lewinski, Jennifer West, Naomi Halas, Rebekah Drezek

JBO, Vol. 10, Issue 06, 064035, (November 2005) https://doi.org/10.1117/12.10.1117/1.2141825

KEYWORDS: Tissue optics, Gold, Scattering, Absorption, Nanoparticles, Particles, Reflectivity, Monte Carlo methods, Optical properties, Tissues

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Proceedings Article | 8 October 2005 Paper

Simulation of oblique-incidence probe geometries for depth-resolved fluorescence spectroscopy

J. Pfefer, A. Agrawal, R. Drezek

Proceedings Volume 5862, 58620Q (2005) https://doi.org/10.1117/12.633031

KEYWORDS: Fluorescence spectroscopy, Signal attenuation, Luminescence, Signal detection, Monte Carlo methods, Tissue optics, Tissues, Optical properties, Photodetectors, Natural surfaces

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Proceedings Article | 7 October 2005 Paper

Quantitative evaluation of nanoshells as a contrast agent for optical coherence tomography

Anant Agrawal, Stanley Huang, Min-Ho Lee, T. Pfefer, Rebekah Drezek

Proceedings Volume 5861, 58610X (2005) https://doi.org/10.1117/12.632991

KEYWORDS: Optical coherence tomography, Scattering, Gold, Tissues, Signal attenuation, Absorption, Backscatter, Biomedical optics, Nanoparticles, Light scattering

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SPIE Journal Paper | 1 July 2005 Open Access

Depth-sensitive reflectance measurements using obliquely oriented fiber probes

Adrien Wang, Janelle Bender, Josh Pfefer, Urs Utzinger, Rebekah Drezek

JBO, Vol. 10, Issue 04, 044017, (July 2005) https://doi.org/10.1117/12.10.1117/1.1989335

KEYWORDS: Reflectivity, Tissue optics, Photons, Tissues, Natural surfaces, Monte Carlo methods, Glasses, Fiber optics, Index matching antireflective coatings, Signal detection

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SPIE Journal Paper | 1 July 2005 Open Access

Oblique-incidence illumination and collection for depth-selective fluorescence spectroscopy

Josh Pfefer, Anant Agrawal, Rebekah Drezek

JBO, Vol. 10, Issue 04, 044016, (July 2005) https://doi.org/10.1117/12.10.1117/1.1989308

KEYWORDS: Signal attenuation, Signal detection, Fluorescence spectroscopy, Tissue optics, Luminescence, Photons, Optical properties, Monte Carlo methods, Tissues, Interfaces

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Proceedings Article | 25 April 2005 Paper

Laser tissue soldering with near-infrared absorbing nanoparticles

Andre Gobin, D. O'Neal, Naomi Halas, Rebekah Drezek, Jennifer West

Proceedings Volume 5686, (2005) https://doi.org/10.1117/12.590614

KEYWORDS: Gold, Tissues, Laser welding, Laser tissue interaction, Absorption, Nanoparticles, Near infrared, Tissue optics, Wound healing, Silica

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Proceedings Article | 23 March 2005 Paper

Depth-sensitive reflectance measurements using obliquely oriented fiber probes

Adrien Wang, Janelle Bender, T. Pfefer, Urs. Utzinger, Rebekah Drezek

Proceedings Volume 5691, (2005) https://doi.org/10.1117/12.593655

KEYWORDS: Reflectivity, Tissue optics, Photons, Tissues, Natural surfaces, Monte Carlo methods, Fiber optics, Glasses, Signal detection, Index matching antireflective coatings

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Proceedings Article | 7 March 2005 Paper

Endogenous fluorescence emission of the ovary

Urs Utzinger, Nathaniel Kirkpatrick, Rebekah Drezek, Molly Brewer

Proceedings Volume 5702, (2005) https://doi.org/10.1117/12.591378

KEYWORDS: Ovarian cancer, Cancer, Luminescence, Ovary, Biopsy, Ultraviolet radiation, Tissues, Tissue optics, Principal component analysis, Fluorescence spectroscopy

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Proceedings Article | 29 December 2004 Paper

Nanoshells for integrated diagnosis and therapy of cancer

Alex Lin, Christopher Loo, Leon Hirsch, Jennifer Barton, Min-Ho Lee, Naomi Halas, Jennifer West, Rebekah Drezek

Proceedings Volume 5593, (2004) https://doi.org/10.1117/12.570267

KEYWORDS: Gold, Scattering, Optical coherence tomography, Cancer, Tissue optics, Near infrared, Absorption, Nanoparticles, Tumors, Biomedical optics

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Proceedings Article | 1 July 2004 Paper

Nanoshells as an optical coherence tomography contrast agent

Jennifer Barton, Naomi Halas, Jennifer West, Rebekah Drezek

Proceedings Volume 5316, (2004) https://doi.org/10.1117/12.529235

KEYWORDS: Optical coherence tomography, Skin, Tissues, Scattering, In vivo imaging, Gold, Signal attenuation, Nanoparticles, Near infrared, In vitro testing

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Proceedings Article | 16 June 2004 Paper

Nanoshell bioconjugates for integrated imaging and therapy of cancer

Christopher Loo, Min-Ho Lee, Leon Hirsch, Jennifer West, Naomi Halas, Rebekah Drezek

Proceedings Volume 5327, (2004) https://doi.org/10.1117/12.553184

KEYWORDS: Cancer, Gold, Near infrared, Silver, Molecular imaging, In vivo imaging, Scattering, In vitro testing, Silica, Nanoparticles

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Proceedings Article | 10 June 2004 Paper

Computational analysis of beveled-tip fiber probes for selective detection of subsurface fluorophores in turbid media

T. Joshua Pfefer, Anant Agrawal, Rebekah Drezek

Proceedings Volume 5317, (2004) https://doi.org/10.1117/12.546520

KEYWORDS: Luminescence, Signal attenuation, Fluorescence spectroscopy, Tissue optics, Monte Carlo methods, Tissues, Optical properties, Fiber optics, Signal detection, Natural surfaces

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SPIE Journal Paper | 1 May 2004 Open Access

Analytical model to describe fluorescence spectra of normal and preneoplastic epithelial tissue: comparison with Monte Carlo simulations and clinical measurements

Sung Chang, Dizem Arifler, Rebekah Drezek, Michelle Follen, Rebecca Richards-Kortum

JBO, Vol. 9, Issue 03, (May 2004) https://doi.org/10.1117/12.10.1117/1.1695559

KEYWORDS: Luminescence, Tissue optics, Monte Carlo methods, Scattering, Tissues, Fluorescence spectroscopy, Absorption, Optical properties, Light scattering, Geometrical optics

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SPIE Journal Paper | 1 January 2003 Open Access

Light scattering from cervical cells throughout neoplastic progression: influence of nuclear morphology, DNA content, and chromatin texture

Rebekah Drezek, Martial Guillaud, Thomas Collier, Iouri Boiko, Anais Malpica, Calum MacAulay, Michele Follen, Rebecca Richards-Kortum

JBO, Vol. 8, Issue 01, (January 2003) https://doi.org/10.1117/12.10.1117/1.1528950

KEYWORDS: Scattering, Light scattering, Refractive index, Tissues, Finite-difference time-domain method, Data modeling, Reflectivity, Confocal microscopy, Tissue optics, Scatter measurement

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SPIE Journal Paper | 1 July 2002 Open Access

Contrast agents for confocal microscopy: how simple chemicals affect confocal images of normal and cancer cells in suspension

Andres Zuluaga, Rebekah Drezek, Thomas Collier, Rueben Lotan, Michele Follen, Rebecca Richards-Kortum

JBO, Vol. 7, Issue 03, (July 2002) https://doi.org/10.1117/12.10.1117/1.1481047

KEYWORDS: Confocal microscopy, Cancer, Phase contrast, Iodine, Scattering, Tissues, Backscatter, In vivo imaging, Clocks, Image segmentation

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SPIE Journal Paper | 1 October 2001 Open Access

Understanding the contributions of NADH and collagen to cervical tissue fluorescence spectra: modeling, measurements, and implications

Rebekah Drezek, Konstantin Sokolov, Urs Utzinger, Iouri Boiko, Anais Malpica, Michele Follen, Rebecca Richards-Kortum

JBO, Vol. 6, Issue 04, (October 2001) https://doi.org/10.1117/12.10.1117/1.1413209

KEYWORDS: Luminescence, Tissues, Collagen, Monte Carlo methods, Absorption, Data modeling, Tissue optics, Optical properties, In vivo imaging, Photons

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SPIE Journal Paper | 1 October 1998 Open Access

Near Real Time Confocal Microscopy of Cultured Amelanotic Cells: Sources of Signal, Contrast Agents and Limits of Contrast

Colin Smithpeter, Andrew Dunn, Rebekah Drezek, Thomas Collier, Rebecca Richards-Kortum

JBO, Vol. 3, Issue 04, (October 1998) https://doi.org/10.1117/12.10.1117/1.429853

KEYWORDS: Confocal microscopy, Scattering, Microscopes, Light scattering, In vivo imaging, Breast cancer, Optical spheres, Tissues, Phase contrast, Image resolution

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Proceedings Article | 26 February 1997 Paper

Active contour based on the elliptical Fourier series, applied to matrix-array ultrasound of the heart

Rebekah Drezek, George Stetten, Takahira Ota, Craig Fleishman, Eric Lily, Cleveland Lewis, Chikai Ohazama, Thomas Ryan, Donald Glower, Joseph Kisslo, Olaf von Ramm

Proceedings Volume 2962, (1997) https://doi.org/10.1117/12.267836

KEYWORDS: Ultrasonography, Heart, 3D image processing, Computer programming, In vivo imaging, Detection and tracking algorithms, Transducers, Fourier transforms, Biomedical engineering, Medical imaging modalities

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