The Luminex xMAPTM system couples bioassays with advanced digital signal processing and proprietary identification
techniques to perform multi-analyte testing of up to 100 features in real time. The general configuration of an xMAP
assay can be described as a suspension array where specific capture moieties are covalently coupled to the surfaces of
internally dyed microspheres. Fluorescent dyes contained within the microspheres provide unique spectral characteristics
allowing each microsphere set to be distinguished from all others in the multiplex. The target is labeled for fluorescent
detection. Here we describe examples of rapid, multiplexed protein and nucleic acid analyses for infectious and biothreat
agents that demonstrate the utility of the platform. Benefits of the system include speed, economy, flexibility, and
advanced capabilities. The potential for simultaneous detection of tens, hundreds, and even thousands of protein and
nucleic acid targets provides for simultaneous, rapid, sensitive, and specific molecular analyses.
Conference Committee Involvement (4)
Optically Based Biological and Chemical Detection for Defence V
1 September 2009 | Berlin, Germany
Optically Based Biological and Chemical Detection for Defence IV
16 September 2008 | Cardiff, Wales, United Kingdom
Optically Based Biological and Chemical Detection for Defence
18 September 2007 | Florence, Italy
Optically-Based Biological and Chemical Detection for Defence III
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