Dr. Stephen J. Lockett Profile

Dr. Stephen J. Lockett

Image Analysis Lab Head at Frederick National Lab for Cancer Research

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Author

Publications (8)

Proceedings Article | 25 February 2010 Paper

Automatic image analysis method for quantification of tube formation by endothelial cells in vitro

De Chen, Ruta Motiejunaite, Andrius Kazlauskas, Prabhakar Gudla, Jack Collins, Stephen Lockett

Proceedings Volume 7568, 75681G (2010) https://doi.org/10.1117/12.841290

KEYWORDS: Image segmentation, In vitro testing, Tumors, Image filtering, Phase contrast, Image analysis, Linear filtering, Microscopy, Cancer, In vivo imaging

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Proceedings Article | 19 February 2007 Paper

HiFLO: a high-throughput system for spatial analysis of FISH loci in interphase nuclei

Prabhakar Gudla, J. Collins, K. Meaburn, T. Misteli, S. Lockett

Proceedings Volume 6441, 644119 (2007) https://doi.org/10.1117/12.700817

KEYWORDS: Image segmentation, Image processing, Statistical analysis, Image processing algorithms and systems, Algorithm development, 3D image processing, Spatial analysis, Image analysis, Biological research, Luminescence

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Proceedings Article | 28 May 2002 Paper

FRAP model to determine the bidirectional transport rate of GFP across the nuclear membrane and the mobile fraction in the cytoplasm and nucleus

Sylvain Costes, Olga Slobodskaya, Edward Cho, Maria Tsopanomihalou-nglotsu, George Pavlakis, Stephen Lockett

Proceedings Volume 4622, (2002) https://doi.org/10.1117/12.468359

KEYWORDS: Proteins, Luminescence, Green fluorescent protein, Image acquisition, Diffusion, Principal component analysis, Digital image correlation, Mathematical modeling, Fluorescent proteins, Image analysis

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Proceedings Article | 27 April 2000 Paper

Analysis of the 3D spatial organization of cells and subcellular structures in tissue

David Knowles, Carlos Ortiz de Solorzano, Arthur Jones, Stephen Lockett

Proceedings Volume 3921, (2000) https://doi.org/10.1117/12.384235

KEYWORDS: Image segmentation, Tissues, 3D image processing, Statistical analysis, Luminescence, 3D acquisition, Electronic design automation, Confocal fluorescent microscopy, Confocal microscopy, Breast

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Proceedings Article | 29 April 1998 Paper

Interactive system for registering adjacent tissue sections

Stephen Lockett, Carlos Fernandez, Enrique Rodriguez, Ulrich Wesselmann, Boris Bastian, Damir Sudar, Daniel Pinkel, Joe Gray

Proceedings Volume 3260, (1998) https://doi.org/10.1117/12.307090

KEYWORDS: Tissues, Composites, Image registration, Microscopes, Video, Visualization, Image acquisition, Molecules, 3D image processing, Tissue optics

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Proceedings Article | 23 March 1995 Paper

Interactive algorithms for rapid enumeration of hybridization signals in individual whole-cell nuclei inside intact-tissue specimens

Stephen Lockett, Curtis Thompson, James Mullikin, Damir Sudar, R. Khavari, William Hyun, Daniel Pinkel, Joe Gray

Proceedings Volume 2412, (1995) https://doi.org/10.1117/12.205346

KEYWORDS: 3D image processing, 3D displays, Algorithm development, Information operations, Silicon, Tissues, Confocal microscopy, Acquisition tracking and pointing, Breast cancer, Evolutionary algorithms

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Proceedings Article | 29 July 1993 Paper

Characterization of a 3D microscope imaging system

Steven Poon, Stephen Lockett, Rabab Ward

Proceedings Volume 1905, (1993) https://doi.org/10.1117/12.148626

KEYWORDS: Point spread functions, Objectives, Imaging systems, Optical transfer functions, Microscopes, Luminescence, Cameras, 3D image processing, Convolution, Microscopy

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Proceedings Article | 26 June 1992 Paper

Application of 3-D digital deconvolution to optically sectioned images for improving the automatic analysis of fluorescent-labeled tumor specimens

Stephen Lockett, Kenneth Jacobson, Brian Herman

Proceedings Volume 1660, (1992) https://doi.org/10.1117/12.59548

KEYWORDS: 3D image processing, Point spread functions, Image segmentation, Detection and tracking algorithms, Breast, Image processing, Tumors, Microscopy, Confocal microscopy, CCD cameras

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Showing 5 of 8 publications

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