With the advancement of technology and medicine, X-ray CT has been widely used in medical diagnosis, treatment, and monitoring of diseases. This article aims to further optimize the performance of X-ray fluorescence CT system by studying the relationship between contrast-to-noise ratio and the concentration and size of regions of interest (ROI). Using Geant4 XFCT simulation modeling, this study analyzes the impact of ROI concentration and size on the quality of XFCT reconstructed images. To assess the influence of different ROI concentrations on imaging performance of the X-ray fluorescence CT system, the simulation modeling system was adjusted for different ROI sizes, and twenty experimental groups were conducted. The results indicate that ROI concentration and size have a significant impact on imaging quality. Under specific conditions of concentration and size within the region of interest, optimal imaging effects of X-ray fluorescence CT can be achieved. These two factors interact, and when adjusting the parameters of ROI concentration and size to optimize imaging quality, it is necessary to consider the changes in both parameters rather than just the influence of a single parameter.
X-ray fluorescence computed tomography (XFCT), as a non-invasive imaging technique, has attracted much attention for its simulation and reconstruction. In this study, we built a simulation model of cone-beam X-ray fluorescence CT using Geant4 and simulated the propagation and interaction process of X-rays in the phantom by Monte Carlo simulation. Then, we acquired the projection data and used the FDK (Feldkamp-Davis-Kress) resolution algorithm to reconstruct the images in three dimensions. The results show that cone-beam X-ray fluorescence CT combined with the FDK algorithm can effectively reconstruct the images, which provides strong support for non-invasive imaging and trace element distribution analysis.
Access to the requested content is limited to institutions that have purchased or subscribe to SPIE eBooks.
You are receiving this notice because your organization may not have SPIE eBooks access.*
*Shibboleth/Open Athens users─please
sign in
to access your institution's subscriptions.
To obtain this item, you may purchase the complete book in print or electronic format on
SPIE.org.
INSTITUTIONAL Select your institution to access the SPIE Digital Library.
PERSONAL Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.