Mr. Linfeng Yang Profile

Linfeng Yang

at Stanford Univ

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Proceedings Article | 10 September 2019 Paper

Low-dose CT via deep CNN with skip connection and network-in-network

Chenyu You, Linfeng Yang, Yi Zhang, Ge Wang

Proceedings Volume 11113, 111131W (2019) https://doi.org/10.1117/12.2534960

KEYWORDS: Denoising, Image quality, Image processing, Computed tomography, Machine learning, Artificial intelligence

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A major challenge in computed tomography (CT) is how to minimize patient radiation exposure without compromising image quality and diagnostic performance. The use of deep convolutional (Conv) neural networks for noise reduction in Low-Dose CT (LDCT) images has recently shown a great potential in this important application. In this paper, we present a highly efficient and effective neural network model for LDCT image noise reduction. Specifically, to capture local anatomical features we integrate Deep Convolutional Neural Networks (CNNs) and Skip connection layers for feature extraction. Also, we introduce parallelized 1 × 1 CNN, called Network in Network, to lower the dimensionality of the output from the previous layer, achieving faster computational speed at less feature loss. To optimize the performance of the network, we adopt a Wasserstein generative adversarial network (WGAN) framework. Quantitative and qualitative comparisons demonstrate that our proposed network model can produce images with lower noise and more structural details than state-of-the-art noise-reduction methods.

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