Dr. Serge L. Muller Profile

Dr. Serge L. Muller

Chief Scientist, Global Women’s Health at GE Healthcare

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Author

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Company Website | Personal Website

Publications (35)

Proceedings Article | 13 July 2022 Paper

Development of a 3D model of clinically relevant microcalcifications

Ann-Katherine Carton, Clement Jailin, Raoul De Silva, Ruben Sanchez De la Rosa, Serge Muller

Proceedings Volume 12286, 1228602 (2022) https://doi.org/10.1117/12.2625771

KEYWORDS: Principal component analysis, 3D modeling, Databases, 3D image processing, Image segmentation, Shape analysis, Performance modeling, Breast, Mammography

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Proceedings Article | 13 July 2022 Paper

Lesion detection in contrast enhanced spectral mammography

Clément Jailin, Pablo Milioni, Zhijin Li, Răzvan Iordache, Serge Muller

Proceedings Volume 12286, 122860A (2022) https://doi.org/10.1117/12.2624577

KEYWORDS: Breast, Diagnostics, Data modeling, Mammography, Computer aided diagnosis and therapy, Cancer, Image classification

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Proceedings Article | 13 July 2022 Paper

Breast shape estimation and correction in CESM biopsy

Ruben Sanchez De La Rosa, Clément Jailin, Ann-Katherine Carton, Pablo Milioni, Laurence Casteignau, Serge Muller

Proceedings Volume 12286, 122860H (2022) https://doi.org/10.1117/12.2625779

KEYWORDS: Breast, Biopsy, Biological research, Image quality, X-rays, Iodine, X-ray imaging, Motion models, Mammography, 3D modeling

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Proceedings Article | 22 May 2020 Paper

Evaluation of the visual realism of breast texture phantoms in digital mammography

Stoyko Marinov, Ann-Katherine Carton, Lesley Cockmartin, Nicholas Marshall, Chantal Van Ongeval, Rubèn Sanchez De la Rosa, Serge Muller, Hilde Bosmans

Proceedings Volume 11513, 1151314 (2020) https://doi.org/10.1117/12.2564124

KEYWORDS: Digital breast tomosynthesis, Breast, Visualization, Digital mammography, Mammography, Medicine

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Proceedings Article | 22 May 2020 Paper

Full-size anthropomorphic phantom for 2D and 3D breast x-ray imaging

James Mainprize, Gordon Mawdsley, Ann-Katherine Carton, Zhijin Li, Remy Klausz, Serge Muller, Martin Yaffe

Proceedings Volume 11513, 1151302 (2020) https://doi.org/10.1117/12.2560358

KEYWORDS: Breast, Tissues, Mammography, Signal attenuation, X-rays, 3D image processing, X-ray imaging, Image processing, Computed tomography, Laser sintering

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Proceedings Article | 9 March 2018 Paper

Simulation of breast compression using a new biomechanical model

Anna Mîra, Yohan Payan, Ann-Katherine Carton, Pablo Milioni de Carvalho, Zhijin Li, Viviane Devauges, Serge Muller

Proceedings Volume 10573, 105735A (2018) https://doi.org/10.1117/12.2293488

KEYWORDS: Breast, Image quality, Mammography, 3D modeling

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Proceedings Article | 9 March 2018 Presentation + Paper

Development of a physical 3D anthropomorphic breast texture model using selective laser sintering rapid prototype printing

James Mainprize, Ann-Katherine Carton, Remy Klausz, Zhijin Li, David Hunter, Gordon Mawdsley, Serge Muller, Martin Yaffe

Proceedings Volume 10573, 105730A (2018) https://doi.org/10.1117/12.2293560

KEYWORDS: Breast, 3D modeling, Printing, Tissues, Signal attenuation, Image segmentation, Laser sintering, Mammography, Digital breast tomosynthesis

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Proceedings Article | 7 March 2018 Presentation + Paper

Comparison of microcalcification detectability in FFDM and DBT using a virtual clinical trial

Zhijin Li, Agnès Desolneux, Serge Muller, Pablo Milioni de Carvalho, Ann-Katherine Carton

Proceedings Volume 10577, 105770D (2018) https://doi.org/10.1117/12.2293619

KEYWORDS: Digital breast tomosynthesis, Signal attenuation, Breast, Image processing, Clinical trials, X-ray imaging, X-rays, Data modeling, Image acquisition, 3D image processing

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Proceedings Article | 18 March 2015 Paper

Clinical image benefits after model-based reconstruction for low dose dedicated breast tomosynthesis

Eri Haneda, J. Eric Tkaczyk, Giovanni Palma, Răzvan Iordache, Serge Muller, Bruno De Man

Proceedings Volume 9412, 94120A (2015) https://doi.org/10.1117/12.2080970

KEYWORDS: Data modeling, Digital breast tomosynthesis, Breast, Model-based design, Sensors, Optical spheres, 3D modeling, Medical imaging, 3D image processing, Breast imaging

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Proceedings Article | 18 March 2015 Paper

Influence of DBT reconstruction algorithm on power law spectrum coefficient

Laurence Vancamberg, Ann-Katherine Carton, Ilyes Abderrahmane, Giovanni Palma, Pablo Milioni de Carvalho, Răzvan Iordache, Serge Muller

Proceedings Volume 9412, 941236 (2015) https://doi.org/10.1117/12.2081969

KEYWORDS: Reconstruction algorithms, Digital breast tomosynthesis, Breast, X-ray imaging, Error analysis, X-rays, Image filtering, Spatial frequencies, Signal to noise ratio, Mammography

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Proceedings Article | 17 March 2015 Paper

The effect of NPS calculation method on power-law coefficient estimation accuracy in breast texture modeling

Zhijin Li, Ann-Katherine Carton, Serge Muller, Răzvan Iordache, Agnès Desolneux

Proceedings Volume 9416, 94161I (2015) https://doi.org/10.1117/12.2081764

KEYWORDS: Breast, X-ray imaging, Error analysis, 3D image processing, Mathematical modeling, Image analysis, Numerical simulations, Digital breast tomosynthesis, Image processing, Convolution

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In breast X-ray imaging, breast texture has been characterized by a radial noise power spectrum (NPS) that has an inverse power-law shape with exponent β. The technique to estimate the radial power-law coefficient β is typically based on averaging 2-dimensional noise power spectra (NPS), calculated from partly overlapping image regions each weighted by a suitable window function. The linear regression applied over a selected frequency range to the logarithm of the 1- dimensional NPS as a function of the logarithm of the radial frequencies, gives β. For each step in this process, several alternative techniques have been proposed. This paper investigates the effect of image region of interest (ROI) size, image data windowing and alternative ways to determine radial frequency in terms of bias, variance and root mean square error (RMSE) in the estimated β. The effects of these three factors were analytically derived and evaluated using synthetic images with known β varying from 1 to 4 to cover the range of textures encountered in 2D and 3D breast X-ray imaging. Our results indicate that the RMSE in estimated β is smallest when the ROIs are multiplied with an appropriate window function and either no radial averaging or radial averaging with small frequency bins is applied. The ROI size yielding the smallest RMSE depends on several factors and needs to be validated with numerical simulations. In clinical practice however, there might be a need to compromise in the choice of the ROI size to balance between the RMSE magnitudes inherent to the applied β estimation technique and encompass the breast texture range so as to obtain an accurate shape of the NPS. When using 2.56 cm x 2.56 cm ROI sizes, applying a 2D Hann window and no radial frequency averaging, the RMSE in the estimated β ranges from 0.04 to 0.1 for true β values equal to 1 and 4. While many subtleties in real images were not modeled to simplify the mathematics in deriving our results, this work is illustrative in demonstrating the limits of commonly used algorithm steps to estimate accurate β values.

Proceedings Article | 17 March 2015 Paper

Assessment of mass detection performance in contrast enhanced digital mammography

Ann-Katherine Carton, Pablo de Carvalho, Zhijin Li, Clarisse Dromain, Serge Muller

Proceedings Volume 9416, 941608 (2015) https://doi.org/10.1117/12.2081772

KEYWORDS: Breast, Iodine, Performance modeling, Tissues, Computer simulations, Mammography, Mathematical modeling, Digital mammography, Magnesium, Medicine

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SPIE Journal Paper | 30 December 2014

Optimization of contrast-enhanced spectral mammography depending on clinical indication

Clarisse Dromain, Sandra Canale, Sylvie Saab-Puong, Ann-Katherine Carton, Serge Muller, Eva Maria Fallenberg

JMI, Vol. 1, Issue 03, 033506, (December 2014) https://doi.org/10.1117/12.10.1117/1.JMI.1.3.033506

KEYWORDS: Image quality, Mammography, Iodine, Image quality standards, Gold, Breast, Biopsy, X-rays, Magnesium, Polymethylmethacrylate

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Proceedings Article | 19 March 2014 Paper

Toward a dose reduction strategy using model-based reconstruction with limited-angle tomosynthesis

Eri Haneda, J. Tkaczyk, Giovanni Palma, Răzvan Iordache, Scott Zelakiewicz, Serge Muller, Bruno De Man

Proceedings Volume 9033, 90330V (2014) https://doi.org/10.1117/12.2042897

KEYWORDS: Signal attenuation, Digital breast tomosynthesis, Sensors, Reconstruction algorithms, Optical spheres, Model-based design, Breast, Data modeling, Computed tomography, Tissues

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Proceedings Article | 6 March 2013 Paper

Spectra optimization for dual-energy contrast-enhanced breast CT

Pablo Milioni de Carvalho, Ann-Katherine Carton, Sylvie Saab-Puong, Răzvan Iordache, Serge Muller

Proceedings Volume 8668, 86681Z (2013) https://doi.org/10.1117/12.2006911

KEYWORDS: Breast, Iodine, Tissues, Sensors, Monte Carlo methods, X-rays, Spatial resolution, Magnesium, Denoising, Spherical lenses

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Proceedings Article | 9 March 2012 Paper

Impact of image acquisition timing on image quality for dual energy contrast-enhanced breast tomosynthesis

Melissa Hill, James Mainprize, Sylvie Puong, Ann-Katherine Carton, Razvan Iordache, Serge Muller, Martin Yaffe

Proceedings Volume 8313, 831308 (2012) https://doi.org/10.1117/12.911627

KEYWORDS: Iodine, Reconstruction algorithms, Image quality, Breast, Image acquisition, X-rays, X-ray imaging, Mammography, Digital breast tomosynthesis, Image enhancement

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Proceedings Article | 16 March 2011 Paper

Effects of image lag and scatter for dual-energy contrast-enhanced digital breast tomosynthesis using a CsI flat-panel based system

Ann-Katherine Carton, Sylvie Puong, Razvan Iordache, Serge Muller

Proceedings Volume 7961, 79611D (2011) https://doi.org/10.1117/12.877941

KEYWORDS: Breast, X-rays, Sensors, Tissues, X-ray imaging, Digital breast tomosynthesis, Imaging systems, Image quality, Digital imaging, Iodine

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Proceedings Article | 2 March 2011 Paper

3D density estimation in digital breast tomosynthesis: application to needle path planning for breast biopsy

Laurence Vancamberg, Nausikaa Geeraert, Razvan Iordache, Giovanni Palma, Rémy Klausz, Serge Muller

Proceedings Volume 7964, 79640D (2011) https://doi.org/10.1117/12.878169

KEYWORDS: Digital breast tomosynthesis, Breast, 3D modeling, Tissues, Binary data, 3D image processing, Biopsy, 3D acquisition, Reconstruction algorithms, X-rays

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Proceedings Article | 19 March 2010 Paper

Triple-energy contrast enhanced digital mammography

Sylvie Puong, Pablo Milioni de Carvalho, Serge Muller

Proceedings Volume 7622, 762208 (2010) https://doi.org/10.1117/12.843776

KEYWORDS: Iodine, Breast, Molybdenum, Optical filters, Tissues, Mammography, Digital mammography, X-rays, Electroluminescence, X-ray imaging

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Proceedings Article | 14 March 2009 Paper

Dual-energy contrast enhanced digital mammography: theoretical and experimental study of optimal monoenergetic beam parameters using synchrotron radiation

Sylvie Puong, Razvan Iordache, Xavier Bouchevreau, Serge Muller

Proceedings Volume 7258, 72583U (2009) https://doi.org/10.1117/12.811596

KEYWORDS: Image quality, Iodine, Breast, Sensors, Tissues, Synchrotron radiation, Digital mammography, Mammography, Image enhancement, Signal attenuation

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Proceedings Article | 3 March 2009 Paper

Detection of convergence areas in digital breast tomosynthesis using a contrario modeling

G. Palma, S. Muller, I. Bloch, R. Iordache

Proceedings Volume 7260, 72600P (2009) https://doi.org/10.1117/12.807547

KEYWORDS: Digital breast tomosynthesis, Medical imaging, Computer aided diagnosis and therapy, Current controlled current source, Architectural distortion, Databases, Breast

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Proceedings Article | 18 March 2008 Paper

Optimization of beam parameters and iodine quantification in dual-energy contrast enhanced digital breast tomosynthesis

Sylvie Puong, Xavier Bouchevreau, Nicolas Duchateau, Razvan Iordache, Serge Muller

Proceedings Volume 6913, 69130Z (2008) https://doi.org/10.1117/12.770148

KEYWORDS: Iodine, Breast, Sensors, Point spread functions, Signal attenuation, Image quality, X-rays, Digital breast tomosynthesis, Tissues, Digital mammography

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Proceedings Article | 17 March 2008 Paper

Masses classification using fuzzy active contours and fuzzy decision trees

G. Palma, G. Peters, S. Muller, I. Bloch

Proceedings Volume 6915, 691509 (2008) https://doi.org/10.1117/12.770078

KEYWORDS: Fuzzy logic, Databases, Particles, Digital breast tomosynthesis, Breast, Image segmentation, Computer aided diagnosis and therapy, Error analysis, Mammography, Feature extraction

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Proceedings Article | 30 March 2007 Paper

Fast microcalcification detection on digital breast tomosynthesis datasets

S. Bernard, S. Muller, G. Peters, R. Iordache

Proceedings Volume 6514, 65141X (2007) https://doi.org/10.1117/12.709987

KEYWORDS: Optical spheres, Digital breast tomosynthesis, Breast, Wavelets, Calcium, Signal attenuation, Sensors, Visualization, Tissues, Convolution

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Proceedings Article | 30 March 2007 Paper

A hybrid active contour model for mass detection in digital breast tomosynthesis

Gero Peters, Serge Muller, Bénédicte Grosjean, Sylvain Bernard, Isabelle Bloch

Proceedings Volume 6514, 65141V (2007) https://doi.org/10.1117/12.709593

KEYWORDS: Image segmentation, Digital breast tomosynthesis, Breast, Data modeling, Mammography, Image filtering, Wavelets, Solid modeling, 3D modeling, Visualization

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Proceedings Article | 21 March 2007 Paper

Dual-energy contrast enhanced digital mammography using a new approach for breast tissue canceling

Sylvie Puong, Xavier Bouchevreau, Fanny Patoureaux, Razvan Iordache, Serge Muller

Proceedings Volume 6510, 65102H (2007) https://doi.org/10.1117/12.710133

KEYWORDS: Iodine, Breast, Algorithm development, Tissues, Image quality, Digital mammography, Detection and tracking algorithms, Computer simulations, X-rays, Calibration

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Proceedings Article | 21 March 2007 Paper

Dual-energy contrast enhanced digital breast tomosynthesis: concept, method, and evaluation on phantoms

Sylvie Puong, Fanny Patoureaux, Razvan Iordache, Xavier Bouchevreau, Serge Muller

Proceedings Volume 6510, 65100U (2007) https://doi.org/10.1117/12.710106

KEYWORDS: Iodine, Reconstruction algorithms, Breast, Digital breast tomosynthesis, Tomography, Manganese, X-rays, Sensors, Signal to noise ratio, Visibility

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Proceedings Article | 8 March 2007 Paper

Tools and methods for exposure control optimization in digital mammography in presence of texture

Bénédicte Grosjean, Serge Muller, Henri Souchay

Proceedings Volume 6515, 651518 (2007) https://doi.org/10.1117/12.709797

KEYWORDS: Breast, Mammography, Signal detection, Image quality, Digital mammography, Tumor growth modeling, Image processing, Rhodium, Imaging systems, X-rays

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Proceedings Article | 17 March 2006 Paper

Lesion detection using an a-contrario detector in simulated digital mammograms

Bénédicte Grosjean, Serge Muller, Henri Souchay

Proceedings Volume 6146, 61460S (2006) https://doi.org/10.1117/12.654140

KEYWORDS: Breast, Mammography, Signal detection, Sensors, Image filtering, Mathematical modeling, Digital mammography, Image processing, X-rays, Monte Carlo methods

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Proceedings Article | 10 March 2006 Paper

Micro-calcification detection in digital tomosynthesis mammography

Frederick Wheeler, A. G. Amitha Perera, Bernhard Claus, Serge Muller, Gero Peters, John Kaufhold

Proceedings Volume 6144, 614420 (2006) https://doi.org/10.1117/12.653478

KEYWORDS: Tissues, Signal detection, 3D modeling, Signal attenuation, Digital mammography, 3D image processing, Sensors, Mammography, Quantum electronics, X-rays

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Proceedings Article | 10 March 2006 Paper

Reconstruction-independent 3D CAD for mass detection in digital breast tomosynthesis using fuzzy particles

G. Peters, S. Muller, S. Bernard, R. Iordache, I. Bloch

Proceedings Volume 6144, 61441Z (2006) https://doi.org/10.1117/12.653633

KEYWORDS: Particles, Fuzzy logic, Digital breast tomosynthesis, Image processing, Reconstruction algorithms, Computer aided design, Mammography, 3D image processing, Wavelets, Databases

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Proceedings Article | 5 June 2003 Paper

Controlling gray-level variation in contrast-enhanced digital mammography: design of a calibration procedure

Fanny Jeunehomme, Razvan Iordache, Serge Muller, Gordon Mawdsley, Martin Yaffe

Proceedings Volume 5030, (2003) https://doi.org/10.1117/12.480485

KEYWORDS: Calibration, Iodine, Breast, Digital mammography, Sensors, Tissues, Mammography, Tumors, X-ray sources, X-ray imaging

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Proceedings Article | 22 May 2003 Paper

Automated scoring of CDMAM: a dose study

Ruben Rico, Serge Muller, Guillaume Peter, Alain Noel, Joseph Stines

Proceedings Volume 5034, (2003) https://doi.org/10.1117/12.480362

KEYWORDS: Image quality, Mammography, Digital mammography, Gold, Signal detection, Image display, Imaging systems, Image processing, Image quality standards, Medical imaging

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Proceedings Article | 3 May 2002 Paper

Contrast-enhanced digital mammography (CEDM): phantom experiment and first clinical results

Christiane Marx, Mirijam Facius, Serge Muller, Karim Benali, Ansgar Malich, Werner Kaiser

Proceedings Volume 4682, (2002) https://doi.org/10.1117/12.465556

KEYWORDS: Iodine, Breast, Digital mammography, Tumors, Mammography, X-rays, Visibility, Signal detection, Magnetic resonance imaging, Signal attenuation

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Proceedings Article | 3 May 2002 Paper

Selection of technique factors for contrast digital mammography

Mia Skarpathiotakis, Stewart Bright, Martin Yaffe, Fanny Jeunehomme, Serge Muller, James Mainprize

Proceedings Volume 4682, (2002) https://doi.org/10.1117/12.465558

KEYWORDS: Breast, Iodine, Code division multiplexing, X-rays, Digital mammography, Tissues, Copper, Molybdenum, Mammography, Tumors

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Showing 5 of 35 publications

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