Radially polarized tip-enhanced near-field coherent anti-Stokes Raman scattering microscopy for bioimaging

Jian Lin; Kenneth Er; Zhiwei Huang

doi:10.1117/12.908476

2 February 2012 Radially polarized tip-enhanced near-field coherent anti-Stokes Raman scattering microscopy for bioimaging

Jian Lin, Kenneth Er, Zhiwei Huang

Author Affiliations +

Proceedings Volume 8231, Nanoscale Imaging, Sensing, and Actuation for Biomedical Applications VIII; 82310B (2012) https://doi.org/10.1117/12.908476
Event: SPIE BiOS, 2012, San Francisco, California, United States

Abstract

CARS is meritorious in its ability to perform chemical selective imaging, but its spatial resolution is limited by the diffraction limit of light; however, this limit can be broken by combining CARS and near-field scanning microscope. In this work, we report a novel radially polarized near-field coherent anti-Stokes Raman scattering microscopy (RP-NF-CARS), which uses radially polarized light as excitation to enhance the electric field enhancement under a metallic tip, and improves the signal to background ratio compared with that using linearly polarized excitations. We applied RP-NF-CARS to image nano-scale polystyrene beads and biological system.

Citation Download Citation

Jian Lin, Kenneth Er, and Zhiwei Huang "Radially polarized tip-enhanced near-field coherent anti-Stokes Raman scattering microscopy for bioimaging", Proc. SPIE 8231, Nanoscale Imaging, Sensing, and Actuation for Biomedical Applications VIII, 82310B (2 February 2012); https://doi.org/10.1117/12.908476

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